PRMT5 Circular RNA Promotes Metastasis of Urothelial Carcinoma of the Bladder through Sponging miR-30c to Induce Epithelial-Mesenchymal Transition

Circular RNAs (circRNAs), a novel class of noncoding RNAs, have recently drawn lots of attention in the pathogenesis of human cancers. However, the role of circRNAs in cancer cells epithelial-mesenchymal transition (EMT) remains unclear. In this study, we aimed to identify novel circRNAs that regula...

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Vydáno v:	Clinical cancer research Ročník 24; číslo 24; s. 6319
Hlavní autoři:	Chen, Xin, Chen, Ri-Xin, Wei, Wen-Su, Li, Yong-Hong, Feng, Zi-Hao, Tan, Lei, Chen, Jie-Wei, Yuan, Gang-Jun, Chen, Si-Liang, Guo, Sheng-Jie, Xiao, Kang-Hua, Liu, Zhuo-Wei, Luo, Jun-Hang, Zhou, Fang-Jian, Xie, Dan
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 15.12.2018
Témata:	Cadherins - metabolism Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - pathology Cell Line, Tumor Computational Biology - methods Epithelial-Mesenchymal Transition - genetics Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Silencing Humans MicroRNAs - genetics Protein-Arginine N-Methyltransferases - genetics RNA RNA Interference RNA, Circular Signal Transduction Snail Family Transcription Factors - genetics Snail Family Transcription Factors - metabolism Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology
ISSN:	1557-3265, 1557-3265
On-line přístup:	Zjistit podrobnosti o přístupu
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