Cytotoxic and apoptosis-inducing effects of novel 8-amido isocoumarin derivatives against breast cancer cells

Isocoumarin is a lactone, a type of natural organic compound that is used as synthetic intermediates of several natural products and pharmaceutical compounds explored for their potential therapeutic applications like antifungal, antimicrobial, anti-inflammatory, and anticancer activities. In our pre...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology Jg. 394; H. 7; S. 1437 - 1449
Hauptverfasser:	Das, Vishal, Kaishap, Partha Pratim, Duarah, Gauri, Chikkaputtaiah, Channakeshavaiah, Deka Boruah, Hari Prasanna, Pal, Mintu
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2021 Springer Nature B.V
Schlagworte:	Annexin V Antifungal agents Antineoplastic Agents - toxicity Apoptosis Apoptosis - drug effects Apoptosis - physiology Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - pathology Cell Survival - drug effects Cell Survival - physiology Cytotoxicity Cytotoxins - toxicity Dose-Response Relationship, Drug Flow cytometry Humans Inflammation Intermediates Isocoumarins - toxicity MCF-7 Cells Natural products Neurosciences Organic compounds Original Article Pharmacology/Toxicology Scanning electron microscopy Therapeutic applications Flow cytometry DAPI-PI dual staining Hematoxylin and eosin staining 8-Amido isocoumarin derivatives MTT assay Scanning electron microscope
ISSN:	0028-1298, 1432-1912, 1432-1912
Online-Zugang:	Volltext
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