Comparison of pharmacokinetics and safety of albuvirtide in healthy subjects after intravenous drip and bolus injection

Albuvirtide (ABT) is the first long-acting HIV fusion inhibitor developed in China, blocking the invasion of HIV-1 virus into target cells. This study aimed to compare the pharmacokinetics (PK), tolerability, and safety of ABT following a single intravenous (IV) bolus injection or intravenous drip i...

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Bibliographic Details
Published in:	Naunyn-Schmiedeberg's archives of pharmacology Vol. 397; no. 2; pp. 913 - 922
Main Authors:	Qin, Huiling, Yao, Cheng, Zhang, Wei, Hu, Wei, Liu, Yuantao, Yu, Shuchang, Xie, Dong, Hu, Min, Ye, Jun
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2024 Springer Nature B.V
Subjects:	Biomedical and Life Sciences Biomedicine Enzyme-linked immunosorbent assay Healthy Volunteers HIV Human immunodeficiency virus Humans Infusions, Intravenous Injection Injections, Intravenous Intravenous administration Maleimides Neurosciences Peptides Pharmacokinetics Pharmacology/Toxicology Bolus injection Bioequivalence Pharmacokinetics Albuvirtide
ISSN:	0028-1298, 1432-1912, 1432-1912
Online Access:	Get full text
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