Disulfiram: a novel repurposed drug for cancer therapy

Cancer is a major health issue worldwide and the global burden of cancer is expected to reduce the costs of treatment as well as prolong the survival time. One of the promising approaches is drug repurposing, because it reduces costs and shortens the production cycle of research and development. Dis...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology Jg. 87; H. 2; S. 159 - 172
Hauptverfasser:	Lu, Chen, Li, Xinyan, Ren, Yongya, Zhang, Xiao
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2021 Springer Nature B.V
Schlagworte:	Alcoholism Aldehyde dehydrogenase Brain cancer Breast cancer Cancer Research Cancer therapies Cell death Chemotherapy Clinical trials Disulfiram Drug abuse Endoplasmic reticulum Glioblastoma Hepatocytes Immobilization Intracellular signalling Liver cancer Localization Medicine Medicine & Public Health Melanoma Metastases NF-κB protein Non-small cell lung carcinoma Oncology Pancreatic cancer Phagocytosis Pharmacology/Toxicology Proteasomes Radiation Review Article Signal transduction Stem cells Tumors Disulfiram Clinical trials Tumour Cancer stem cells
ISSN:	0344-5704, 1432-0843, 1432-0843
Online-Zugang:	Volltext
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