Five-Year Outcomes of Sleeve Gastrectomy in Patients with Class I Obesity and Type 2 Diabetes Mellitus

Background Several studies have reported short and medium-term outcomes of laparoscopic sleeve gastrectomy (LSG) in patients with class I obesity and type 2 diabetes mellitus (T2DM). However, literature on outcomes beyond three years is scarce. The present study discusses the 5-year results of a pre...

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Vydáno v:Obesity surgery Ročník 32; číslo 1; s. 96 - 102
Hlavní autoři: Singh, Devender, Baksi, Aditya, Ramana, Prasanna, Singla, Vitish, Aggarwal, Sandeep
Médium: Journal Article
Jazyk:angličtina
Vydáno: New York Springer US 01.01.2022
Springer Nature B.V
Témata:
Adult
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - surgery
Female
Gastrectomy - methods
Gastrointestinal surgery
Glycated Hemoglobin - metabolism
Humans
Laparoscopy
Laparoscopy - methods
Male
Medicine
Medicine & Public Health
Middle Aged
Obesity
Obesity - surgery
Obesity, Morbid - surgery
Original Contributions
Retrospective Studies
Surgery
Treatment Outcome
Weight control
Weight Loss
Long-term outcomes
T2DM
Metabolic surgery
Bariatric surgery
Non-severe obesity
ISSN:0960-8923, 1708-0428, 1708-0428
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Shrnutí:Background Several studies have reported short and medium-term outcomes of laparoscopic sleeve gastrectomy (LSG) in patients with class I obesity and type 2 diabetes mellitus (T2DM). However, literature on outcomes beyond three years is scarce. The present study discusses the 5-year results of a previously reported cohort of 20 patients with class I obesity and T2DM, who had undergone LSG between March 2012 and March 2015. Materials and Methods Patients were followed up in the bariatric clinic at yearly intervals as per institute protocol. Primary outcome was proportion of patients with a glycated haemoglobin (HbA1c) level of 6.5% or less, 5 years after LSG. Secondary outcomes were percentage total weight loss (%TWL), excess weight loss (EWL), weight regain and complications. Results Out of 20 patients, 9 (45%) were male and 11 (55%) were female. Mean age was 41.6 ± 9.5 years. Mean pre-operative weight and BMI were 94.8 ± 14.4 kg and 33.4 ± 1.2 kg/m 2 , respectively. Median duration of diabetes was 42 months. Mean pre-operative fasting plasma glucose (FPG) and HbA1c were 171.1 ± 56.8 mg/dL and 8.7 ± 1.6%, respectively. Of the 17 patients available for follow-up at 5 years, 9 (52.9%) achieved HbA1c < 6.5% without medication, while 7 (41.2%) patients had improvement of their glycaemic status. One patient had recurrence of diabetes after initial remission. Mean %TWL and %EWL were 18% and 65.1%, respectively. Conclusion Laparoscopic sleeve gastrectomy is a reasonable option as a metabolic procedure for patients with T2DM and class I obesity. Graphical abstract
Bibliografie:ObjectType-Article-1
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ISSN:0960-8923
1708-0428
1708-0428
DOI:10.1007/s11695-021-05718-x