Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations

Mutations in the BRCA1 and BRCA2 tumour suppressor genes are associated with prostate cancer risk; however, optimal screening protocols for individuals with these mutations have been a subject of debate. Several prospective studies of prostate cancer incidence and screening among BRCA1/2 mutation ca...

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Bibliographic Details
Published in:	Nature reviews. Urology Vol. 20; no. 4; pp. 205 - 216
Main Authors:	Rajwa, Pawel, Quhal, Fahad, Pradere, Benjamin, Gandaglia, Giorgio, Ploussard, Guillaume, Leapman, Michael S, Gore, John L, Paradysz, Andrzej, Tilki, Derya, Merseburger, Axel S, Morgan, Todd M, Briganti, Alberto, Palapattu, Ganesh S, Shariat, Shahrokh F
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.04.2023
Subjects:	BRCA1 Protein - genetics BRCA2 Protein - genetics Early Detection of Cancer - methods Genes, BRCA1 Genetic Predisposition to Disease Germ Cells - pathology Humans Male Medical screening Mutation Prospective Studies Prostate cancer Prostate-Specific Antigen - genetics Prostatic Neoplasms - diagnosis Prostatic Neoplasms - genetics Prostatic Neoplasms - therapy Quality of Life
ISSN:	1759-4812, 1759-4820, 1759-4820
Online Access:	Get full text
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