Involvement of cytochrome P450 enzymes in inflammation and cancer: a review

Cytochrome P450 (CYP) enzymes are responsible for the biotransformation of drugs, xenobiotics, and endogenous substances. This enzymatic activity can be modulated by intrinsic and extrinsic factors, modifying the organism’s response to medications. Among the factors that are responsible for enzyme i...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology Jg. 87; H. 3; S. 295 - 309
Hauptverfasser:	Stipp, Maria Carolina, Acco, Alexandra
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2021 Springer Nature B.V
Schlagworte:	Biotransformation Breast cancer Cancer Cancer Research Carcinogenesis Cell survival Chemotherapy Cytochrome Cytochrome P450 Cytokines Enzymatic activity Enzymes Hepatocellular carcinoma Inflammation Interleukin 1 Interleukin 6 Leukocytes (neutrophilic) Liver cancer Lung cancer Lymphocytes Macrophages Medicine Medicine & Public Health Mutation Oncology Pharmacology/Toxicology Review Article Toxicity Tumor microenvironment Tumor necrosis factor-TNF Tumor necrosis factor-α Xenobiotics γ-Interferon Chemotherapy Hepatocarcinoma Breast cancer CYP450 Enzyme Lung cancer
ISSN:	0344-5704, 1432-0843, 1432-0843
Online-Zugang:	Volltext
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