Opioid-Induced Tolerance and Hyperalgesia

Opioids are very potent and efficacious drugs, traditionally used for both acute and chronic pain conditions. However, the use of opioids is frequently associated with the occurrence of adverse effects or clinical problems. Other than adverse effects and dependence, the development of tolerance is a...

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Veröffentlicht in:	CNS drugs Jg. 33; H. 10; S. 943 - 955
Hauptverfasser:	Mercadante, Sebastiano, Arcuri, Edoardo, Santoni, Angela
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Cham Springer International Publishing 01.10.2019 Springer Nature B.V
Schlagworte:	Adaptation Analgesia Analgesics Anesthetics Chronic pain Current Opinion Drug dosages Drug tolerance Drug withdrawal Hyperalgesia Hypersensitivity Local anesthetics Medicine Medicine & Public Health Morphine Mortality Narcotics Neurology Neurosciences Opioids Pain Pain perception Patients Pharmacotherapy Psychiatry Psychopharmacology Side effects Substance abuse treatment
ISSN:	1172-7047, 1179-1934, 1179-1934
Online-Zugang:	Volltext
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