ROS production by mitochondria: function or dysfunction?

In eukaryotic cells, ATP generation is generally viewed as the primary function of mitochondria under normoxic conditions. Reactive oxygen species (ROS), in contrast, are regarded as the by-products of respiration, and are widely associated with dysfunction and disease. Important signaling functions...

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Bibliographic Details

Published in:	Oncogene Vol. 43; no. 5; pp. 295 - 303
Main Authors:	Palma, Flavio R., Gantner, Benjamin N., Sakiyama, Marcelo J., Kayzuka, Cezar, Shukla, Sanjeev, Lacchini, Riccardo, Cunniff, Brian, Bonini, Marcelo G.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 29.01.2024 Nature Publishing Group
Subjects:	631/45 631/67/2327 Apoptosis Cell Biology Human Genetics Internal Medicine Medicine Medicine & Public Health Mitochondria Oncology Reactive oxygen species Review Article
ISSN:	0950-9232, 1476-5594, 1476-5594
Online Access:	Get full text
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