ROS production by mitochondria: function or dysfunction?

In eukaryotic cells, ATP generation is generally viewed as the primary function of mitochondria under normoxic conditions. Reactive oxygen species (ROS), in contrast, are regarded as the by-products of respiration, and are widely associated with dysfunction and disease. Important signaling functions...

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Veröffentlicht in:	Oncogene Jg. 43; H. 5; S. 295 - 303
Hauptverfasser:	Palma, Flavio R., Gantner, Benjamin N., Sakiyama, Marcelo J., Kayzuka, Cezar, Shukla, Sanjeev, Lacchini, Riccardo, Cunniff, Brian, Bonini, Marcelo G.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 29.01.2024 Nature Publishing Group
Schlagworte:	631/45 631/67/2327 Apoptosis Cell Biology Human Genetics Internal Medicine Medicine Medicine & Public Health Mitochondria Oncology Reactive oxygen species Review Article
ISSN:	0950-9232, 1476-5594, 1476-5594
Online-Zugang:	Volltext
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