Formulation development and evaluation of therapeutic contact lens loaded with ganciclovir

Purpose In the present investigation ganciclovir (GAN) loaded microparticles dispersed in hydrogel-based contact lenses were fabricated, characterized and evaluated for eye irritation. Methods GAN-Hydroxy Propyl Methyl Cellulose (HPMC) microparticles were prepared by solvent evaporation method and e...

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Bibliographic Details
Published in:	International ophthalmology Vol. 43; no. 7; pp. 2225 - 2236
Main Authors:	Harsolekar, Mohit, Ansari, Mudassir, Supe, Shibani, Singh, Kavita
Format:	Journal Article
Language:	English
Published:	Dordrecht Springer Netherlands 01.07.2023 Springer Nature B.V
Subjects:	Animals Antiviral drugs Cellulose Chickens Chorioallantoic membrane Contact lenses Contact Lenses, Hydrophilic Drug delivery Drug Delivery Systems - methods Entrapment Evaporation Eye Female Free radical polymerization Free radicals Ganciclovir Hydrogels Irritation Medicine Medicine & Public Health Membrane permeability Methylcellulose Microparticles Morphology Ophthalmology Original Paper Permeability Photoinitiators Polyhydroxyethyl methacrylate Swelling Transmittance Ganciclovir Free radical polymerization Hydrogel Soft contact lenses Microparticles
ISSN:	1573-2630, 0165-5701, 1573-2630
Online Access:	Get full text
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