Polygenic scores in cancer

Since the publication of the first genome-wide association study for cancer in 2007, thousands of common alleles that are associated with the risk of cancer have been identified. The relative risk associated with individual variants is small and of limited clinical significance. However, the combine...

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Vydané v:	Nature reviews. Cancer Ročník 23; číslo 9; s. 619 - 630
Hlavní autori:	Yang, Xin, Kar, Siddhartha, Antoniou, Antonis C, Pharoah, Paul D P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England Nature Publishing Group 01.09.2023
Predmet:	Alleles Cancer Clinical Relevance Clinical trials Genome-wide association studies Genome-Wide Association Study Genomes Humans Neoplasms - genetics Prediction models Reviews Therapeutic applications
ISSN:	1474-175X, 1474-1768, 1474-1768
On-line prístup:	Získať plný text
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