Challenges and opportunities for omics-based precision medicine in chronic low back pain

Purpose Chronic low back pain (cLBP) is a common health condition worldwide and a leading cause of disability with an estimated lifetime prevalence of 80–90% in industrialized countries. However, we have had limited success in treating cLBP likely due to its non-specific heterogeneous nature that go...

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Bibliographic Details
Published in:	European spine journal Vol. 34; no. 7; pp. 2522 - 2536
Main Authors:	Firdous, Ayesha, Gopalakrishnan, Vanathi, Vo, Nam, Sowa, Gwendolyn
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2025 Springer Nature B.V
Subjects:	Antigens Back pain Chronic pain Chronic Pain - diagnosis Chronic Pain - genetics Chronic Pain - metabolism Chronic Pain - therapy Diagnosis Disease Genomes Genomics Genomics - methods Humans Inflammation Information processing Low back pain Low Back Pain - diagnosis Low Back Pain - genetics Low Back Pain - metabolism Low Back Pain - therapy Medical diagnosis Medicine Medicine & Public Health Neurosurgery Pathophysiology Patients Polymorphism Precision medicine Precision Medicine - methods Proteomics Proteomics - methods Single-nucleotide polymorphism Supplement Article Surgical Orthopedics Therapeutic targets Transcriptomics United States > US Chronic low back pain Precision medicine Multi-omics Omics
ISSN:	0940-6719, 1432-0932, 1432-0932
Online Access:	Get full text
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