The Long Non-coding RNA NEAT1/miR-224-5p/IL-33 Axis Modulates Macrophage M2a Polarization and A1 Astrocyte Activation

To identify potential regulators and investigate the molecular mechanism of macrophage polarization affecting astrocyte activation from the perspective of non-coding RNA regulation, we isolated mouse bone marrow mononuclear cells (BMMNCs)–induced macrophages toward M1 or M2a polarization. Long non-c...

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Veröffentlicht in:	Molecular neurobiology Jg. 58; H. 9; S. 4506 - 4519
Hauptverfasser:	Liu, Dongliang, Wei, Yuehua, Liu, Yudong, Wu, Tianding, Hu, Jianzhong, Lu, Hongbin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Springer US 01.09.2021 Springer Nature B.V
Schlagworte:	Animals Astrocytes Astrocytes - cytology Astrocytes - metabolism Biomedical and Life Sciences Biomedicine Bone marrow Cell activation Cell Biology Cell Polarity Interleukin 13 Interleukin 4 Interleukin-33 - metabolism Kinases Leukocytes (mononuclear) Macrophage Activation Macrophages Macrophages - cytology Macrophages - metabolism Mice MicroRNAs - metabolism Neurobiology Neurology Neurosciences Non-coding RNA Polarization Proteins RNA, Long Noncoding - metabolism Signal Transduction - physiology miR-224-5p Macrophage polarization IL-33 Long non-coding RNA NEAT1 A1 astrocyte activation
ISSN:	0893-7648, 1559-1182, 1559-1182
Online-Zugang:	Volltext
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