Residual dynamics resolves recurrent contributions to neural computation

Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerabl...

Celý popis

Uložené v:

Podrobná bibliografia
Vydané v:	Nature neuroscience Ročník 26; číslo 2; s. 326 - 338
Hlavní autori:	Galgali, Aniruddh R., Sahani, Maneesh, Mante, Valerio
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	New York Nature Publishing Group US 01.02.2023 Nature Publishing Group
Predmet:	631/378/116/1925 631/378/116/2393 631/378/2649/1409 Animal Genetics and Genomics Animals Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Circuits Decision making Dynamics Macaca Mental task performance Neurobiology Neurosciences Perturbation Prefrontal Cortex Saccades Saccadic eye movements
ISSN:	1097-6256, 1546-1726, 1546-1726
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!

Abstract	Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals—that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations. Activity in a neural population arises from both its inputs and its recurrent connections. Here the authors show that analyzing the dynamics of trial-to-trial variability in activity can offer insights into delineating these contributions.
AbstractList	Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals—that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations.Activity in a neural population arises from both its inputs and its recurrent connections. Here the authors show that analyzing the dynamics of trial-to-trial variability in activity can offer insights into delineating these contributions. Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals-that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations.Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals-that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations. Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals-that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations. Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently connected neural populations. However, inferring the nature of recurrent dynamics from partial recordings of a neural circuit presents considerable challenges. Here we show that some of these challenges can be overcome by a fine-grained analysis of the dynamics of neural residuals—that is, trial-by-trial variability around the mean neural population trajectory for a given task condition. Residual dynamics in macaque prefrontal cortex (PFC) in a saccade-based perceptual decision-making task reveals recurrent dynamics that is time dependent, but consistently stable, and suggests that pronounced rotational structure in PFC trajectories during saccades is driven by inputs from upstream areas. The properties of residual dynamics restrict the possible contributions of PFC to decision-making and saccade generation and suggest a path toward fully characterizing distributed neural computations with large-scale neural recordings and targeted causal perturbations. Activity in a neural population arises from both its inputs and its recurrent connections. Here the authors show that analyzing the dynamics of trial-to-trial variability in activity can offer insights into delineating these contributions.
Author	Galgali, Aniruddh R. Mante, Valerio Sahani, Maneesh
Author_xml	– sequence: 1 givenname: Aniruddh R. orcidid: 0000-0002-0509-8225 surname: Galgali fullname: Galgali, Aniruddh R. email: aniruddh.galgali@psy.ox.ac.uk organization: Institute of Neuroinformatics, University of Zurich & ETH Zurich, Neuroscience Center Zurich, University of Zurich & ETH Zurich, Department of Experimental Psychology, University of Oxford – sequence: 2 givenname: Maneesh orcidid: 0000-0001-5560-3341 surname: Sahani fullname: Sahani, Maneesh organization: Gatsby Computational Neuroscience Unit, University College London – sequence: 3 givenname: Valerio orcidid: 0000-0003-3412-4215 surname: Mante fullname: Mante, Valerio email: valerio@ini.uzh.ch organization: Institute of Neuroinformatics, University of Zurich & ETH Zurich, Neuroscience Center Zurich, University of Zurich & ETH Zurich
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/36635498$$D View this record in MEDLINE/PubMed
BookMark	eNp9kU1LJDEQhoOM-DG7f2AP0uDFS6-V7-6jyK4KAwui55BO0ktLdzImHcF_b8Z2V_Awl6QIz5Mq6j1FKx-8Q-gHhp8YaHOZGOYtrYGQGjChUJMDdII5EzWWRKxKDa2sBeHiGJ2m9AQAkjftETqmQlDO2uYE3d67NNisx8q-ej0NJlXRpTC-uF1hcozOz5UJfo5Dl-ch-FTNofIux-KYMG3zrHfP39Bhr8fkvn_ca_T4-9fD9W29-XNzd321qQ2VfK6Z6YgR2gkODHeWctP3HZe2t4B7yoDyTlqNLbemZ1x2HehyWkkabHrQjq7RxfLvNobn7NKspiEZN47au5CTIlJwKQUjbUHPv6BPIUdfpiuUZABctjvq7IPK3eSs2sZh0vFV_dtRAcgCmBhSiq7_j2BQuyDUEoQqQaj3IBQpUvNFMsOyqDnqYdyv0kVNpY__6-Ln2HusNwtmnZA
CitedBy_id	crossref_primary_10_1038_s41592_024_02582_2 crossref_primary_10_1371_journal_pcbi_1013081 crossref_primary_10_7554_eLife_93060 crossref_primary_10_1038_s41583_023_00740_7 crossref_primary_10_1016_j_physrep_2023_10_005 crossref_primary_10_1038_s41467_024_54688_y crossref_primary_10_1038_s41593_024_01845_7 crossref_primary_10_1126_science_adp7429 crossref_primary_10_7554_eLife_93060_3 crossref_primary_10_1088_1741_2552_ad1053 crossref_primary_10_1371_journal_pcbi_1011852 crossref_primary_10_3389_fnins_2025_1582080 crossref_primary_10_1038_s41593_023_01445_x crossref_primary_10_1038_s41593_024_01668_6 crossref_primary_10_1038_s41586_025_09199_1 crossref_primary_10_1016_j_conb_2023_102759 crossref_primary_10_1038_s41593_024_01704_5 crossref_primary_10_1038_s41586_025_09528_4 crossref_primary_10_1523_JNEUROSCI_1733_24_2025 crossref_primary_10_1523_JNEUROSCI_0462_23_2023
Cites_doi	10.1038/nn.4042 10.1162/NECO_a_00953 10.1016/j.neuron.2018.07.003 10.1016/j.neuron.2008.12.012 10.1038/s41593-020-0696-5 10.1257/jep.15.4.69 10.1016/j.neuron.2008.09.034 10.7554/eLife.52460 10.1016/j.neuron.2019.06.012 10.1016/j.pneurobio.2013.02.002 10.1016/j.neuron.2019.08.025 10.1038/nn.4433 10.1038/s41593-019-0555-4 10.1073/pnas.1818972116 10.1016/j.neuron.2022.05.011 10.1038/nn.3405 10.1038/s41586-019-0997-6 10.1038/nature11129 10.1016/j.neuroscience.2005.06.094 10.1038/nn.2842 10.1038/s41593-020-00733-0 10.1038/nature14066 10.1038/s41586-022-04724-y 10.1523/JNEUROSCI.4761-07.2008 10.1016/j.neuron.2015.02.014 10.1152/jn.00613.2012 10.1016/j.neuron.2018.04.017 10.1038/s41586-019-1869-9 10.1038/s41593-020-0699-2 10.1038/s41593-021-00821-9 10.1038/nn.2501 10.1007/BF01183780 10.1523/JNEUROSCI.3276-09.2010 10.1038/nn.3220 10.1016/j.neuron.2019.01.026 10.1523/JNEUROSCI.12-12-04745.1992 10.1038/nrn3962 10.1523/JNEUROSCI.0343-17.2017 10.1038/s41586-019-0919-7 10.1016/j.neuron.2017.02.019 10.1016/j.neuron.2009.02.005 10.1523/JNEUROSCI.2523-11.2012 10.1523/JNEUROSCI.18-10-03870.1998 10.1038/s41593-019-0460-x 10.1038/nature13665 10.1146/annurev-neuro-092619-094115 10.1038/nature12742 10.1038/nature17643 10.1016/j.neuron.2015.09.008 10.1038/nn.3862 10.1007/BF01386294 10.1016/j.tics.2015.05.004 10.1146/annurev.neuro.29.051605.113038 10.1016/j.neuron.2014.04.045 10.1073/pnas.0804451105 10.1038/nn.3776 10.1038/s41592-018-0109-9 10.1016/j.neuron.2005.09.032 10.1038/nn.3711 10.1152/jn.90941.2008 10.1038/s41586-019-1787-x 10.1214/aoms/1177731868 10.1016/0167-2789(92)90242-F 10.1038/s41467-018-04725-4 10.1038/nature04968 10.1016/j.neuron.2010.12.037 10.1038/nn.3643 10.1007/978-0-387-84858-7 10.1007/1-84628-158-X 10.1101/214262
ContentType	Journal Article
Copyright	The Author(s), under exclusive licence to Springer Nature America, Inc. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
Copyright_xml	– notice: The Author(s), under exclusive licence to Springer Nature America, Inc. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. – notice: 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
DBID	AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7QG 7QP 7QR 7TK 7TM 7U7 7U9 7X7 7XB 88E 88G 8AO 8FD 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI C1K CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ H94 HCIFZ K9. LK8 M0S M1P M2M M7P P64 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS PSYQQ Q9U RC3 7X8
DOI	10.1038/s41593-022-01230-2
DatabaseName	CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Animal Behavior Abstracts Calcium & Calcified Tissue Abstracts Chemoreception Abstracts Neurosciences Abstracts Nucleic Acids Abstracts Toxicology Abstracts Virology and AIDS Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection Environmental Sciences and Pollution Management ProQuest One ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student AIDS and Cancer Research Abstracts SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) ProQuest Biological Science Collection Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Psychology Database Biological Science Database Biotechnology and BioEngineering Abstracts ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China One Psychology ProQuest Central Basic Genetics Abstracts MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student ProQuest Central Essentials Nucleic Acids Abstracts SciTech Premium Collection ProQuest Central China Environmental Sciences and Pollution Management ProQuest One Applied & Life Sciences Health Research Premium Collection Natural Science Collection Health & Medical Research Collection Biological Science Collection Chemoreception Abstracts ProQuest Central (New) ProQuest Medical Library (Alumni) Virology and AIDS Abstracts ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts ProQuest Health & Medical Complete ProQuest One Academic UKI Edition Engineering Research Database ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) Technology Research Database ProQuest One Academic Middle East (New) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central ProQuest Health & Medical Research Collection Genetics Abstracts Health and Medicine Complete (Alumni Edition) ProQuest Central Korea AIDS and Cancer Research Abstracts ProQuest Central Basic Toxicology Abstracts ProQuest Psychology Journals (Alumni) ProQuest SciTech Collection ProQuest Medical Library ProQuest Psychology Journals Animal Behavior Abstracts ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	ProQuest One Psychology MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Anatomy & Physiology
EISSN	1546-1726
EndPage	338
ExternalDocumentID	36635498 10_1038_s41593_022_01230_2
Genre	Research Support, Non-U.S. Gov't Journal Article
GrantInformation_xml	– fundername: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) grantid: PP00P3-157539 funderid: https://doi.org/10.13039/501100001711 – fundername: Simons Foundation grantid: SCGB 328189; SCGB 543013; SCGB 543039; SCGB 543039 funderid: https://doi.org/10.13039/100000893 – fundername: Howard Hughes Medical Institute
GroupedDBID	--- -DZ .55 .GJ 0R~ 123 29M 2FS 36B 39C 3V. 4.4 53G 5BI 5RE 70F 7X7 85S 88E 8AO 8FI 8FJ 8R4 8R5 AAEEF AARCD AAYZH AAZLF ABAWZ ABDBF ABIVO ABJNI ABLJU ABUWG ACBWK ACGFS ACIWK ACNCT ACPRK ACUHS ADBBV AENEX AFBBN AFKRA AFRAH AFSHS AGAYW AGHTU AHBCP AHMBA AHOSX AHSBF AIBTJ ALFFA ALIPV ALMA_UNASSIGNED_HOLDINGS ARMCB ASPBG AVWKF AXYYD AZFZN AZQEC B0M BBNVY BENPR BHPHI BKKNO BPHCQ BVXVI CCPQU CS3 D0L DB5 DU5 DWQXO EAD EAP EBC EBD EBS EE. EJD EMB EMK EMOBN EPL EPS ESX EXGXG F5P FEDTE FQGFK FSGXE FYUFA GNUQQ HCIFZ HMCUK HVGLF HZ~ IAO IGS IHR INH INR IPY ISR ITC M1P M2M M7P MVM N9A NNMJJ O9- ODYON P2P PQQKQ PROAC PSQYO PSYQQ Q2X RNS RNT RNTTT SHXYY SIXXV SNYQT SOJ SV3 TAOOD TBHMF TDRGL TSG TUS UKHRP X7M XJT YNT YQT ZGI ~8M AAYXX ABFSG ACSTC AEZWR AFANA AFFHD AFHIU AGSTI AHWEU AIXLP ALPWD ATHPR CITATION NFIDA PHGZM PHGZT PJZUB PPXIY PQGLB AETEA CGR CUY CVF ECM EIF NPM 7QG 7QP 7QR 7TK 7TM 7U7 7U9 7XB 8FD 8FE 8FH 8FK C1K FR3 H94 K9. LK8 P64 PKEHL PQEST PQUKI PRINS Q9U RC3 7X8 PUEGO
ID	FETCH-LOGICAL-c375t-4cb2c6ae65041bd35cffb57dfd01f34035b7da1d5dcf457bb0a57bd7281cf0ae3
IEDL.DBID	M7P
ISICitedReferencesCount	21
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000937304500017&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1097-6256 1546-1726
IngestDate	Wed Oct 01 13:46:02 EDT 2025 Tue Oct 07 05:40:40 EDT 2025 Tue Mar 18 09:46:15 EDT 2025 Tue Nov 18 22:33:30 EST 2025 Sat Nov 29 05:28:47 EST 2025 Fri Feb 21 02:40:12 EST 2025
IsPeerReviewed	true
IsScholarly	true
Issue	2
Language	English
License	2023. The Author(s), under exclusive licence to Springer Nature America, Inc.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c375t-4cb2c6ae65041bd35cffb57dfd01f34035b7da1d5dcf457bb0a57bd7281cf0ae3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ORCID	0000-0001-5560-3341 0000-0003-3412-4215 0000-0002-0509-8225
PMID	36635498
PQID	2774005799
PQPubID	44706
PageCount	13
ParticipantIDs	proquest_miscellaneous_2765776429 proquest_journals_2774005799 pubmed_primary_36635498 crossref_primary_10_1038_s41593_022_01230_2 crossref_citationtrail_10_1038_s41593_022_01230_2 springer_journals_10_1038_s41593_022_01230_2
PublicationCentury	2000
PublicationDate	2023-02-01
PublicationDateYYYYMMDD	2023-02-01
PublicationDate_xml	– month: 02 year: 2023 text: 2023-02-01 day: 01
PublicationDecade	2020
PublicationPlace	New York
PublicationPlace_xml	– name: New York – name: United States
PublicationTitle	Nature neuroscience
PublicationTitleAbbrev	Nat Neurosci
PublicationTitleAlternate	Nat Neurosci
PublicationYear	2023
Publisher	Nature Publishing Group US Nature Publishing Group
Publisher_xml	– name: Nature Publishing Group US – name: Nature Publishing Group
References	Wald (CR71) 1940; 11 Sani, Abbaspourazad, Wong, Pesaran, Shanechi (CR33) 2021; 24 Chaudhuri, Knoblauch, Gariel, Kennedy, Wang (CR41) 2015; 88 Aoi, Mante, Pillow (CR57) 2020; 23 Bound, Jaeger, Baker (CR72) 1995; 90 CR32 CR74 Laje, Buonomano (CR37) 2013; 16 Hennequin, Ahmadian, Rubin, Lengyel, Miller (CR64) 2018; 98 CR70 Linderman (CR5) 2017; 54 Churchland (CR21) 2010; 13 Britten, Shadlen, Newsome, Movshon (CR66) 1992; 12 Sadtler (CR30) 2014; 512 Libby, Buschman (CR58) 2021; 24 Deco, Jirsa (CR61) 2012; 32 Churchland (CR20) 2011; 69 Ebrahimi (CR25) 2022; 605 Cunningham, Yu (CR3) 2014; 17 Litwin-Kumar, Doiron (CR65) 2012; 15 Shadlen, Newsome (CR19) 1998; 18 CR8 Zhao, Park (CR6) 2017; 29 CR48 Yuste (CR2) 2015; 16 Machens, Romo, Brody (CR43) 2010; 30 Gallego, Perich, Chowdhury, Solla, Miller (CR31) 2020; 23 Sauerbrei (CR18) 2020; 577 Churchland (CR36) 2012; 487 Murphy, Miller (CR45) 2009; 61 Li, Daie, Svoboda, Druckmann (CR26) 2016; 532 Sohn, Narain, Meirhaeghe, Jazayeri (CR14) 2019; 103 Goldman (CR46) 2009; 61 Rudin, Osher, Fatemi (CR73) 1992; 60 Barak, Sussillo, Romo, Tsodyks, Abbott (CR15) 2013; 103 Stokes (CR50) 2015; 19 Hanks (CR55) 2015; 520 Mazor, Laurent (CR10) 2005; 48 Das, Fiete (CR39) 2020; 23 Pandarinath (CR7) 2018; 15 Mante, Sussillo, Shenoy, Newsome (CR12) 2013; 503 Vyas, Golub, Sussillo, Shenoy (CR11) 2020; 43 Pinto (CR17) 2019; 104 Murray, Jaramillo, Wang (CR38) 2017; 37 Durstewitz, Seamans (CR60) 2006; 139 Cedervall, Stoica (CR69) 1996; 15 Hart, Huk (CR54) 2020; 9 Gold, Shadlen (CR42) 2007; 30 Ganguli, Huh, Sompolinsky (CR47) 2008; 105 Javadzadeh, Hofer (CR52) 2022; 110 Kiani, Hanks, Shadlen (CR56) 2008; 28 Rosenbaum, Smith, Kohn, Rubin, Doiron (CR24) 2017; 20 Chettih, Harvey (CR27) 2019; 567 Semedo, Zandvakili, Machens, Yu, Kohn (CR44) 2019; 102 Purcell, Heitz, Cohen, Schall (CR63) 2012; 108 Mastrogiuseppe, Ostojic (CR16) 2018; 99 Inagaki, Fontolan, Romani, Svoboda (CR28) 2019; 566 Henrici (CR75) 1962; 4 Kiani (CR49) 2015; 85 Sussillo, Churchland, Kaufman, Shenoy (CR13) 2015; 18 CR68 Jazayeri, Afraz (CR29) 2017; 93 Wang (CR35) 2008; 60 Yu (CR4) 2009; 102 Wilting, Priesemann (CR40) 2018; 9 Chaudhuri, Gerçek, Pandey, Peyrache, Fiete (CR9) 2019; 22 Murray (CR53) 2014; 17 Hennequin, Vogels, Gerstner (CR59) 2014; 82 Santhanam, Ryu, Yu, Afshar, Shenoy (CR67) 2006; 442 Goris, Movshon, Simoncelli (CR23) 2014; 17 Angrist, Krueger (CR34) 2001; 15 Kaufman, Churchland, Ryu, Shenoy (CR51) 2014; 17 Dahmen, Grün, Diesmann, Helias (CR62) 2019; 116 Cohen, Kohn (CR22) 2011; 14 Steinmetz, Zatka-Haas, Carandini, Harris (CR1) 2019; 576 E Hart (1230_CR54) 2020; 9 NA Steinmetz (1230_CR1) 2019; 576 G Deco (1230_CR61) 2012; 32 MM Churchland (1230_CR21) 2010; 13 M Jazayeri (1230_CR29) 2017; 93 BA Purcell (1230_CR63) 2012; 108 JD Murray (1230_CR53) 2014; 17 D Durstewitz (1230_CR60) 2006; 139 JD Semedo (1230_CR44) 2019; 102 R Rosenbaum (1230_CR24) 2017; 20 JD Murray (1230_CR38) 2017; 37 J Wilting (1230_CR40) 2018; 9 CK Machens (1230_CR43) 2010; 30 PT Sadtler (1230_CR30) 2014; 512 R Chaudhuri (1230_CR41) 2015; 88 RLT Goris (1230_CR23) 2014; 17 R Yuste (1230_CR2) 2015; 16 1230_CR48 AK Churchland (1230_CR20) 2011; 69 G Santhanam (1230_CR67) 2006; 442 G Hennequin (1230_CR59) 2014; 82 MR Cohen (1230_CR22) 2011; 14 X-J Wang (1230_CR35) 2008; 60 BK Murphy (1230_CR45) 2009; 61 SN Chettih (1230_CR27) 2019; 567 D Dahmen (1230_CR62) 2019; 116 R Chaudhuri (1230_CR9) 2019; 22 A Litwin-Kumar (1230_CR65) 2012; 15 A Wald (1230_CR71) 1940; 11 J Bound (1230_CR72) 1995; 90 R Laje (1230_CR37) 2013; 16 TD Hanks (1230_CR55) 2015; 520 N Li (1230_CR26) 2016; 532 O Mazor (1230_CR10) 2005; 48 M Cedervall (1230_CR69) 1996; 15 HK Inagaki (1230_CR28) 2019; 566 F Mastrogiuseppe (1230_CR16) 2018; 99 Y Zhao (1230_CR6) 2017; 29 C Pandarinath (1230_CR7) 2018; 15 M Javadzadeh (1230_CR52) 2022; 110 D Sussillo (1230_CR13) 2015; 18 1230_CR8 MM Churchland (1230_CR36) 2012; 487 LI Rudin (1230_CR73) 1992; 60 S Vyas (1230_CR11) 2020; 43 MG Stokes (1230_CR50) 2015; 19 BM Yu (1230_CR4) 2009; 102 R Kiani (1230_CR56) 2008; 28 OG Sani (1230_CR33) 2021; 24 L Pinto (1230_CR17) 2019; 104 JD Angrist (1230_CR34) 2001; 15 P Henrici (1230_CR75) 1962; 4 A Libby (1230_CR58) 2021; 24 MT Kaufman (1230_CR51) 2014; 17 MN Shadlen (1230_CR19) 1998; 18 JA Gallego (1230_CR31) 2020; 23 SW Linderman (1230_CR5) 2017; 54 H Sohn (1230_CR14) 2019; 103 1230_CR74 1230_CR32 1230_CR70 KH Britten (1230_CR66) 1992; 12 MS Goldman (1230_CR46) 2009; 61 S Ganguli (1230_CR47) 2008; 105 1230_CR68 R Kiani (1230_CR49) 2015; 85 A Das (1230_CR39) 2020; 23 S Ebrahimi (1230_CR25) 2022; 605 G Hennequin (1230_CR64) 2018; 98 JP Cunningham (1230_CR3) 2014; 17 MC Aoi (1230_CR57) 2020; 23 JI Gold (1230_CR42) 2007; 30 V Mante (1230_CR12) 2013; 503 O Barak (1230_CR15) 2013; 103 BA Sauerbrei (1230_CR18) 2020; 577
References_xml	– ident: CR70 – volume: 18 start-page: 1025 year: 2015 end-page: 1033 ident: CR13 article-title: A neural network that finds a naturalistic solution for the production of muscle activity publication-title: Nat. Neurosci. doi: 10.1038/nn.4042 – volume: 29 start-page: 1293 year: 2017 end-page: 1316 ident: CR6 article-title: Variational latent Gaussian process for recovering single-trial dynamics from population spike trains publication-title: Neural Comput. doi: 10.1162/NECO_a_00953 – volume: 99 start-page: 609 year: 2018 end-page: 623 ident: CR16 article-title: Linking connectivity, dynamics, and computations in low-rank recurrent neural networks publication-title: Neuron doi: 10.1016/j.neuron.2018.07.003 – volume: 61 start-page: 621 year: 2009 end-page: 634 ident: CR46 article-title: Memory without feedback in a neural network publication-title: Neuron doi: 10.1016/j.neuron.2008.12.012 – volume: 23 start-page: 1410 year: 2020 end-page: 1420 ident: CR57 article-title: Prefrontal cortex exhibits multidimensional dynamic encoding during decision-making publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-0696-5 – ident: CR68 – ident: CR74 – volume: 15 start-page: 69 year: 2001 end-page: 85 ident: CR34 article-title: Instrumental variables and the search for identification: from supply and demand to natural experiments publication-title: J. Econ. Perspect. doi: 10.1257/jep.15.4.69 – volume: 60 start-page: 215 year: 2008 end-page: 234 ident: CR35 article-title: Decision making in recurrent neuronal circuits publication-title: Neuron doi: 10.1016/j.neuron.2008.09.034 – volume: 9 start-page: e52460 year: 2020 ident: CR54 article-title: Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network publication-title: eLife doi: 10.7554/eLife.52460 – volume: 103 start-page: 934 year: 2019 end-page: 947 ident: CR14 article-title: Bayesian computation through cortical latent dynamics publication-title: Neuron doi: 10.1016/j.neuron.2019.06.012 – volume: 103 start-page: 214 year: 2013 end-page: 222 ident: CR15 article-title: From fixed points to chaos: three models of delayed discrimination publication-title: Prog. Neurobiol. doi: 10.1016/j.pneurobio.2013.02.002 – volume: 104 start-page: 810 year: 2019 end-page: 824 ident: CR17 article-title: Task-dependent changes in the large-scale dynamics and necessity of cortical regions publication-title: Neuron doi: 10.1016/j.neuron.2019.08.025 – volume: 20 start-page: 107 year: 2017 end-page: 114 ident: CR24 article-title: The spatial structure of correlated neuronal variability publication-title: Nat. Neurosci. doi: 10.1038/nn.4433 – volume: 23 start-page: 260 year: 2020 end-page: 270 ident: CR31 article-title: Long-term stability of cortical population dynamics underlying consistent behavior publication-title: Nat. Neurosci. doi: 10.1038/s41593-019-0555-4 – ident: CR8 – volume: 116 start-page: 13051 year: 2019 end-page: 13060 ident: CR62 article-title: Second type of criticality in the brain uncovers rich multiple-neuron dynamics publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1818972116 – volume: 110 start-page: 2470 year: 2022 end-page: 2483 ident: CR52 article-title: Dynamic causal communication channels between neocortical areas publication-title: Neuron doi: 10.1016/j.neuron.2022.05.011 – volume: 90 start-page: 443 year: 1995 end-page: 450 ident: CR72 article-title: Problems with instrumental variables estimation when the correlation between the instruments and the endogenous explanatory variable is weak publication-title: J. Am. Stat. Assoc. – volume: 16 start-page: 925 year: 2013 end-page: 933 ident: CR37 article-title: Robust timing and motor patterns by taming chaos in recurrent neural networks publication-title: Nat. Neurosci. doi: 10.1038/nn.3405 – volume: 567 start-page: 334 year: 2019 end-page: 340 ident: CR27 article-title: Single-neuron perturbations reveal feature-specific competition in V1 publication-title: Nature doi: 10.1038/s41586-019-0997-6 – volume: 487 start-page: 51 year: 2012 end-page: 56 ident: CR36 article-title: Neural population dynamics during reaching publication-title: Nature doi: 10.1038/nature11129 – volume: 139 start-page: 119 year: 2006 end-page: 133 ident: CR60 article-title: Beyond bistability: biophysics and temporal dynamics of working memory publication-title: Neuroscience doi: 10.1016/j.neuroscience.2005.06.094 – volume: 14 start-page: 811 year: 2011 end-page: 819 ident: CR22 article-title: Measuring and interpreting neuronal correlations publication-title: Nat. Neurosci. doi: 10.1038/nn.2842 – volume: 24 start-page: 140 year: 2021 end-page: 149 ident: CR33 article-title: Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-00733-0 – volume: 520 start-page: 220 year: 2015 end-page: 223 ident: CR55 article-title: Distinct relationships of parietal and prefrontal cortices to evidence accumulation publication-title: Nature doi: 10.1038/nature14066 – volume: 605 start-page: 713 year: 2022 end-page: 721 ident: CR25 article-title: Emergent reliability in sensory cortical coding and inter-area communication publication-title: Nature doi: 10.1038/s41586-022-04724-y – volume: 28 start-page: 3017 year: 2008 end-page: 3029 ident: CR56 article-title: Bounded integration in parietal cortex underlies decisions even when viewing duration is dictated by the environment publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.4761-07.2008 – volume: 85 start-page: 1359 year: 2015 end-page: 1373 ident: CR49 article-title: Natural grouping of neural responses reveals spatially segregated clusters in prearcuate cortex publication-title: Neuron doi: 10.1016/j.neuron.2015.02.014 – volume: 108 start-page: 2737 year: 2012 end-page: 2750 ident: CR63 article-title: Response variability of frontal eye field neurons modulates with sensory input and saccade preparation but not visual search salience publication-title: J. Neurophysiol. doi: 10.1152/jn.00613.2012 – volume: 98 start-page: 846 year: 2018 end-page: 860 ident: CR64 article-title: The dynamical regime of sensory cortex: stable dynamics around a single stimulus-tuned attractor account for patterns of noise variability publication-title: Neuron doi: 10.1016/j.neuron.2018.04.017 – volume: 577 start-page: 386 year: 2020 end-page: 391 ident: CR18 article-title: Cortical pattern generation during dexterous movement is input-driven publication-title: Nature doi: 10.1038/s41586-019-1869-9 – ident: CR32 – volume: 23 start-page: 1286 year: 2020 end-page: 1296 ident: CR39 article-title: Systematic errors in connectivity inferred from activity in strongly recurrent networks publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-0699-2 – volume: 24 start-page: 715 year: 2021 end-page: 726 ident: CR58 article-title: Rotational dynamics reduce interference between sensory and memory representations publication-title: Nat. Neurosci. doi: 10.1038/s41593-021-00821-9 – volume: 13 start-page: 369 year: 2010 end-page: 378 ident: CR21 article-title: Stimulus onset quenches neural variability: a widespread cortical phenomenon publication-title: Nat. Neurosci. doi: 10.1038/nn.2501 – volume: 15 start-page: 275 year: 1996 end-page: 290 ident: CR69 article-title: System identification from noisy measurements by using instrumental variables and subspace fitting publication-title: Circuits Syst. Signal Process. doi: 10.1007/BF01183780 – volume: 30 start-page: 350 year: 2010 end-page: 360 ident: CR43 article-title: Functional, but not anatomical, separation of ‘what’ and ‘when’ in prefrontal cortex publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.3276-09.2010 – volume: 15 start-page: 1498 year: 2012 end-page: 1505 ident: CR65 article-title: Slow dynamics and high variability in balanced cortical networks with clustered connections publication-title: Nat. Neurosci. doi: 10.1038/nn.3220 – volume: 102 start-page: 249 year: 2019 end-page: 259 ident: CR44 article-title: Cortical areas interact through a communication subspace publication-title: Neuron doi: 10.1016/j.neuron.2019.01.026 – volume: 12 start-page: 4745 year: 1992 end-page: 4765 ident: CR66 article-title: The analysis of visual motion: a comparison of neuronal and psychophysical performance publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.12-12-04745.1992 – volume: 16 start-page: 487 year: 2015 end-page: 497 ident: CR2 article-title: From the neuron doctrine to neural networks publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn3962 – volume: 37 start-page: 12167 year: 2017 end-page: 12186 ident: CR38 article-title: Working memory and decision-making in a frontoparietal circuit model publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.0343-17.2017 – volume: 566 start-page: 212 year: 2019 end-page: 217 ident: CR28 article-title: Discrete attractor dynamics underlies persistent activity in the frontal cortex publication-title: Nature doi: 10.1038/s41586-019-0919-7 – volume: 93 start-page: 1003 year: 2017 end-page: 1014 ident: CR29 article-title: Navigating the neural space in search of the neural code publication-title: Neuron doi: 10.1016/j.neuron.2017.02.019 – volume: 61 start-page: 635 year: 2009 end-page: 648 ident: CR45 article-title: Balanced amplification: a new mechanism of selective amplification of neural activity patterns publication-title: Neuron doi: 10.1016/j.neuron.2009.02.005 – volume: 32 start-page: 3366 year: 2012 end-page: 3375 ident: CR61 article-title: Ongoing cortical activity at rest: criticality, multistability, and ghost attractors publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2523-11.2012 – volume: 18 start-page: 3870 year: 1998 end-page: 3896 ident: CR19 article-title: The variable discharge of cortical neurons: implications for connectivity, computation, and information coding publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.18-10-03870.1998 – volume: 22 start-page: 1512 year: 2019 end-page: 1520 ident: CR9 article-title: The intrinsic attractor manifold and population dynamics of a canonical cognitive circuit across waking and sleep publication-title: Nat. Neurosci. doi: 10.1038/s41593-019-0460-x – volume: 512 start-page: 423 year: 2014 end-page: 426 ident: CR30 article-title: Neural constraints on learning publication-title: Nature doi: 10.1038/nature13665 – volume: 43 start-page: 249 year: 2020 end-page: 275 ident: CR11 article-title: Computation through neural population dynamics publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev-neuro-092619-094115 – volume: 503 start-page: 78 year: 2013 end-page: 84 ident: CR12 article-title: Context-dependent computation by recurrent dynamics in prefrontal cortex publication-title: Nature doi: 10.1038/nature12742 – volume: 532 start-page: 459 year: 2016 end-page: 464 ident: CR26 article-title: Robust neuronal dynamics in premotor cortex during motor planning publication-title: Nature doi: 10.1038/nature17643 – volume: 54 start-page: 914 year: 2017 end-page: 922 ident: CR5 article-title: Bayesian learning and inference in recurrent switching linear dynamical systems publication-title: Proc. 20th Int. Conf. Artif. Intell. Stat. – volume: 88 start-page: 419 year: 2015 end-page: 431 ident: CR41 article-title: A large-scale circuit mechanism for hierarchical dynamical processing in the primate cortex publication-title: Neuron doi: 10.1016/j.neuron.2015.09.008 – volume: 17 start-page: 1661 year: 2014 end-page: 1663 ident: CR53 article-title: A hierarchy of intrinsic timescales across primate cortex publication-title: Nat. Neurosci. doi: 10.1038/nn.3862 – volume: 4 start-page: 24 year: 1962 end-page: 40 ident: CR75 article-title: Bounds for iterates, inverses, spectral variation and fields of values of non-normal matrices publication-title: Numer. Math. doi: 10.1007/BF01386294 – volume: 19 start-page: 394 year: 2015 end-page: 405 ident: CR50 article-title: ‘Activity-silent’ working memory in prefrontal cortex: a dynamic coding framework publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2015.05.004 – volume: 30 start-page: 535 year: 2007 end-page: 574 ident: CR42 article-title: The neural basis of decision making publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.neuro.29.051605.113038 – volume: 82 start-page: 1394 year: 2014 end-page: 1406 ident: CR59 article-title: Optimal control of transient dynamics in balanced networks supports generation of complex movements publication-title: Neuron doi: 10.1016/j.neuron.2014.04.045 – volume: 105 start-page: 18970 year: 2008 end-page: 18975 ident: CR47 article-title: Memory traces in dynamical systems publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804451105 – volume: 17 start-page: 1500 year: 2014 end-page: 1509 ident: CR3 article-title: Dimensionality reduction for large-scale neural recordings publication-title: Nat. Neurosci. doi: 10.1038/nn.3776 – ident: CR48 – volume: 15 start-page: 805 year: 2018 end-page: 815 ident: CR7 article-title: Inferring single-trial neural population dynamics using sequential auto-encoders publication-title: Nat. Methods doi: 10.1038/s41592-018-0109-9 – volume: 48 start-page: 661 year: 2005 end-page: 673 ident: CR10 article-title: Transient dynamics versus fixed points in odor representations by locust antennal lobe projection neurons publication-title: Neuron doi: 10.1016/j.neuron.2005.09.032 – volume: 17 start-page: 858 year: 2014 end-page: 865 ident: CR23 article-title: Partitioning neuronal variability publication-title: Nat. Neurosci. doi: 10.1038/nn.3711 – volume: 102 start-page: 614 year: 2009 end-page: 635 ident: CR4 article-title: Gaussian-process factor analysis for low-dimensional single-trial analysis of neural population activity publication-title: J. Neurophysiol. doi: 10.1152/jn.90941.2008 – volume: 576 start-page: 266 year: 2019 end-page: 273 ident: CR1 article-title: Distributed coding of choice, action and engagement across the mouse brain publication-title: Nature doi: 10.1038/s41586-019-1787-x – volume: 11 start-page: 284 year: 1940 end-page: 300 ident: CR71 article-title: The fitting of straight lines if both variables are subject to error publication-title: Ann. Math. Stat. doi: 10.1214/aoms/1177731868 – volume: 60 start-page: 259 year: 1992 end-page: 268 ident: CR73 article-title: Nonlinear total variation based noise removal algorithms publication-title: Phys. Nonlinear Phenom. doi: 10.1016/0167-2789(92)90242-F – volume: 9 year: 2018 ident: CR40 article-title: Inferring collective dynamical states from widely unobserved systems publication-title: Nat. Commun. doi: 10.1038/s41467-018-04725-4 – volume: 442 start-page: 195 year: 2006 end-page: 198 ident: CR67 article-title: A high-performance brain–computer interface publication-title: Nature doi: 10.1038/nature04968 – volume: 69 start-page: 818 year: 2011 end-page: 831 ident: CR20 article-title: Variance as a signature of neural computations during decision making publication-title: Neuron doi: 10.1016/j.neuron.2010.12.037 – volume: 17 start-page: 440 year: 2014 end-page: 448 ident: CR51 article-title: Cortical activity in the null space: permitting preparation without movement publication-title: Nat. Neurosci. doi: 10.1038/nn.3643 – volume: 567 start-page: 334 year: 2019 ident: 1230_CR27 publication-title: Nature doi: 10.1038/s41586-019-0997-6 – volume: 23 start-page: 260 year: 2020 ident: 1230_CR31 publication-title: Nat. Neurosci. doi: 10.1038/s41593-019-0555-4 – volume: 23 start-page: 1286 year: 2020 ident: 1230_CR39 publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-0699-2 – volume: 11 start-page: 284 year: 1940 ident: 1230_CR71 publication-title: Ann. Math. Stat. doi: 10.1214/aoms/1177731868 – volume: 104 start-page: 810 year: 2019 ident: 1230_CR17 publication-title: Neuron doi: 10.1016/j.neuron.2019.08.025 – volume: 18 start-page: 3870 year: 1998 ident: 1230_CR19 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.18-10-03870.1998 – volume: 566 start-page: 212 year: 2019 ident: 1230_CR28 publication-title: Nature doi: 10.1038/s41586-019-0919-7 – volume: 103 start-page: 934 year: 2019 ident: 1230_CR14 publication-title: Neuron doi: 10.1016/j.neuron.2019.06.012 – volume: 23 start-page: 1410 year: 2020 ident: 1230_CR57 publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-0696-5 – volume: 88 start-page: 419 year: 2015 ident: 1230_CR41 publication-title: Neuron doi: 10.1016/j.neuron.2015.09.008 – volume: 105 start-page: 18970 year: 2008 ident: 1230_CR47 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.0804451105 – volume: 9 start-page: e52460 year: 2020 ident: 1230_CR54 publication-title: eLife doi: 10.7554/eLife.52460 – volume: 102 start-page: 614 year: 2009 ident: 1230_CR4 publication-title: J. Neurophysiol. doi: 10.1152/jn.90941.2008 – volume: 69 start-page: 818 year: 2011 ident: 1230_CR20 publication-title: Neuron doi: 10.1016/j.neuron.2010.12.037 – volume: 16 start-page: 925 year: 2013 ident: 1230_CR37 publication-title: Nat. Neurosci. doi: 10.1038/nn.3405 – volume: 108 start-page: 2737 year: 2012 ident: 1230_CR63 publication-title: J. Neurophysiol. doi: 10.1152/jn.00613.2012 – volume: 82 start-page: 1394 year: 2014 ident: 1230_CR59 publication-title: Neuron doi: 10.1016/j.neuron.2014.04.045 – volume: 28 start-page: 3017 year: 2008 ident: 1230_CR56 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.4761-07.2008 – volume: 30 start-page: 350 year: 2010 ident: 1230_CR43 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.3276-09.2010 – volume: 503 start-page: 78 year: 2013 ident: 1230_CR12 publication-title: Nature doi: 10.1038/nature12742 – ident: 1230_CR8 – volume: 15 start-page: 805 year: 2018 ident: 1230_CR7 publication-title: Nat. Methods doi: 10.1038/s41592-018-0109-9 – ident: 1230_CR70 doi: 10.1007/978-0-387-84858-7 – volume: 99 start-page: 609 year: 2018 ident: 1230_CR16 publication-title: Neuron doi: 10.1016/j.neuron.2018.07.003 – volume: 15 start-page: 1498 year: 2012 ident: 1230_CR65 publication-title: Nat. Neurosci. doi: 10.1038/nn.3220 – volume: 487 start-page: 51 year: 2012 ident: 1230_CR36 publication-title: Nature doi: 10.1038/nature11129 – volume: 32 start-page: 3366 year: 2012 ident: 1230_CR61 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2523-11.2012 – volume: 577 start-page: 386 year: 2020 ident: 1230_CR18 publication-title: Nature doi: 10.1038/s41586-019-1869-9 – volume: 14 start-page: 811 year: 2011 ident: 1230_CR22 publication-title: Nat. Neurosci. doi: 10.1038/nn.2842 – volume: 116 start-page: 13051 year: 2019 ident: 1230_CR62 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1818972116 – volume: 103 start-page: 214 year: 2013 ident: 1230_CR15 publication-title: Prog. Neurobiol. doi: 10.1016/j.pneurobio.2013.02.002 – volume: 110 start-page: 2470 year: 2022 ident: 1230_CR52 publication-title: Neuron doi: 10.1016/j.neuron.2022.05.011 – volume: 29 start-page: 1293 year: 2017 ident: 1230_CR6 publication-title: Neural Comput. doi: 10.1162/NECO_a_00953 – volume: 60 start-page: 259 year: 1992 ident: 1230_CR73 publication-title: Phys. Nonlinear Phenom. doi: 10.1016/0167-2789(92)90242-F – volume: 442 start-page: 195 year: 2006 ident: 1230_CR67 publication-title: Nature doi: 10.1038/nature04968 – volume: 15 start-page: 275 year: 1996 ident: 1230_CR69 publication-title: Circuits Syst. Signal Process. doi: 10.1007/BF01183780 – volume: 576 start-page: 266 year: 2019 ident: 1230_CR1 publication-title: Nature doi: 10.1038/s41586-019-1787-x – volume: 37 start-page: 12167 year: 2017 ident: 1230_CR38 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.0343-17.2017 – volume: 520 start-page: 220 year: 2015 ident: 1230_CR55 publication-title: Nature doi: 10.1038/nature14066 – volume: 48 start-page: 661 year: 2005 ident: 1230_CR10 publication-title: Neuron doi: 10.1016/j.neuron.2005.09.032 – volume: 61 start-page: 635 year: 2009 ident: 1230_CR45 publication-title: Neuron doi: 10.1016/j.neuron.2009.02.005 – ident: 1230_CR68 doi: 10.1007/1-84628-158-X – volume: 15 start-page: 69 year: 2001 ident: 1230_CR34 publication-title: J. Econ. Perspect. doi: 10.1257/jep.15.4.69 – volume: 43 start-page: 249 year: 2020 ident: 1230_CR11 publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev-neuro-092619-094115 – volume: 102 start-page: 249 year: 2019 ident: 1230_CR44 publication-title: Neuron doi: 10.1016/j.neuron.2019.01.026 – volume: 60 start-page: 215 year: 2008 ident: 1230_CR35 publication-title: Neuron doi: 10.1016/j.neuron.2008.09.034 – volume: 90 start-page: 443 year: 1995 ident: 1230_CR72 publication-title: J. Am. Stat. Assoc. – volume: 512 start-page: 423 year: 2014 ident: 1230_CR30 publication-title: Nature doi: 10.1038/nature13665 – ident: 1230_CR48 doi: 10.1101/214262 – volume: 9 year: 2018 ident: 1230_CR40 publication-title: Nat. Commun. doi: 10.1038/s41467-018-04725-4 – volume: 17 start-page: 858 year: 2014 ident: 1230_CR23 publication-title: Nat. Neurosci. doi: 10.1038/nn.3711 – volume: 93 start-page: 1003 year: 2017 ident: 1230_CR29 publication-title: Neuron doi: 10.1016/j.neuron.2017.02.019 – volume: 30 start-page: 535 year: 2007 ident: 1230_CR42 publication-title: Annu. Rev. Neurosci. doi: 10.1146/annurev.neuro.29.051605.113038 – volume: 24 start-page: 140 year: 2021 ident: 1230_CR33 publication-title: Nat. Neurosci. doi: 10.1038/s41593-020-00733-0 – volume: 139 start-page: 119 year: 2006 ident: 1230_CR60 publication-title: Neuroscience doi: 10.1016/j.neuroscience.2005.06.094 – volume: 22 start-page: 1512 year: 2019 ident: 1230_CR9 publication-title: Nat. Neurosci. doi: 10.1038/s41593-019-0460-x – volume: 85 start-page: 1359 year: 2015 ident: 1230_CR49 publication-title: Neuron doi: 10.1016/j.neuron.2015.02.014 – volume: 4 start-page: 24 year: 1962 ident: 1230_CR75 publication-title: Numer. Math. doi: 10.1007/BF01386294 – volume: 17 start-page: 440 year: 2014 ident: 1230_CR51 publication-title: Nat. Neurosci. doi: 10.1038/nn.3643 – volume: 17 start-page: 1661 year: 2014 ident: 1230_CR53 publication-title: Nat. Neurosci. doi: 10.1038/nn.3862 – volume: 19 start-page: 394 year: 2015 ident: 1230_CR50 publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2015.05.004 – volume: 13 start-page: 369 year: 2010 ident: 1230_CR21 publication-title: Nat. Neurosci. doi: 10.1038/nn.2501 – volume: 61 start-page: 621 year: 2009 ident: 1230_CR46 publication-title: Neuron doi: 10.1016/j.neuron.2008.12.012 – volume: 24 start-page: 715 year: 2021 ident: 1230_CR58 publication-title: Nat. Neurosci. doi: 10.1038/s41593-021-00821-9 – volume: 20 start-page: 107 year: 2017 ident: 1230_CR24 publication-title: Nat. Neurosci. doi: 10.1038/nn.4433 – ident: 1230_CR74 – ident: 1230_CR32 – volume: 54 start-page: 914 year: 2017 ident: 1230_CR5 publication-title: Proc. 20th Int. Conf. Artif. Intell. Stat. – volume: 12 start-page: 4745 year: 1992 ident: 1230_CR66 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.12-12-04745.1992 – volume: 18 start-page: 1025 year: 2015 ident: 1230_CR13 publication-title: Nat. Neurosci. doi: 10.1038/nn.4042 – volume: 532 start-page: 459 year: 2016 ident: 1230_CR26 publication-title: Nature doi: 10.1038/nature17643 – volume: 98 start-page: 846 year: 2018 ident: 1230_CR64 publication-title: Neuron doi: 10.1016/j.neuron.2018.04.017 – volume: 17 start-page: 1500 year: 2014 ident: 1230_CR3 publication-title: Nat. Neurosci. doi: 10.1038/nn.3776 – volume: 605 start-page: 713 year: 2022 ident: 1230_CR25 publication-title: Nature doi: 10.1038/s41586-022-04724-y – volume: 16 start-page: 487 year: 2015 ident: 1230_CR2 publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn3962
SSID	ssj0007589
Score	2.5472164
Snippet	Relating neural activity to behavior requires an understanding of how neural computations arise from the coordinated dynamics of distributed, recurrently...
SourceID	proquest pubmed crossref springer
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	326
SubjectTerms	631/378/116/1925 631/378/116/2393 631/378/2649/1409 Animal Genetics and Genomics Animals Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Circuits Decision making Dynamics Macaca Mental task performance Neurobiology Neurosciences Perturbation Prefrontal Cortex Saccades Saccadic eye movements
Title	Residual dynamics resolves recurrent contributions to neural computation
URI	https://link.springer.com/article/10.1038/s41593-022-01230-2 https://www.ncbi.nlm.nih.gov/pubmed/36635498 https://www.proquest.com/docview/2774005799 https://www.proquest.com/docview/2765776429
Volume	26
WOSCitedRecordID	wos000937304500017&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1546-1726 dateEnd: 20241213 omitProxy: false ssIdentifier: ssj0007589 issn: 1097-6256 databaseCode: M7P dateStart: 20230101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1546-1726 dateEnd: 20241213 omitProxy: false ssIdentifier: ssj0007589 issn: 1097-6256 databaseCode: 7X7 dateStart: 20230101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1546-1726 dateEnd: 20241213 omitProxy: false ssIdentifier: ssj0007589 issn: 1097-6256 databaseCode: BENPR dateStart: 20230101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Psychology Database customDbUrl: eissn: 1546-1726 dateEnd: 20241213 omitProxy: false ssIdentifier: ssj0007589 issn: 1097-6256 databaseCode: M2M dateStart: 20230101 isFulltext: true titleUrlDefault: https://www.proquest.com/psychology providerName: ProQuest
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9wwEB4V6KGXUkpLt8DKlRCX1iKx49g-VRSBOJTVCkG1t8iPREKChJIFqf--Y8e7qELlwiVKFDuxPGPPjOfxAewZqbW1XFNblp4WPmuoESqnjZASDSIviphb9eunnEzUbKan6cCtT2GViz0xbtS-c-GM_IChnhIzJ_X32980oEYF72qC0FiBtVAlgcXQvelyJ0ZdWEdvp5YU9fwyJc1kXB30KLhC5BoLgQmohlP2r2B6om0-8ZRGAXSy_tKhv4O3SfUkhwOvbMCrun0Pm4ctmt03f8g-icGg8ZR9E07P6z6maRE_QNb3BO3y7vqhDjduKOpEYpx7AszqybwjoTom9nERKiLS_ANcnhxfHJ3SBLpAHZdiTgtnmStNjZpbkVvPhWsaK6RvfJY3vMi4sNKb3AvvmkJIazODVy-Zyl2TmZp_hNW2a-tPQASavEzhqs9xApxyJhQWyphxKJid9nIE-WLGK5cqkgdgjOsqesa5qgYqVUilKlKpYiP4uuxzO9TjeLb1zoIiVVqbffVIjhF8Wb7GVRVcJaatu_vQpkRmRdsM22wNDLD8HQ9KWqHVCL4tOOLx4_8fy-fnx7INbwKS_RAQvgOr87v7ehdeu4f5VX83hhU5k_GqxrD243gyPcenM3Y2jhz_F929AVs
linkProvider	ProQuest
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3dT9UwFD9BNNEXRVG5CloT9UUbtm5d1wdCiEou4XJjDBreRr-WkMCGdwNz_yn_Rk-77RJD5I0HX5Yla7uP_nr6OztfAG-VkFLrRFKdZZamNiqp4nlMSy4EKkSWpyG26sdETKf50ZH8ugS_h1gY71Y5yMQgqG1t_D_yTYY8JUROyu3zn9RXjfLW1aGERgeLfTf_hSpbs7X3Gef3HWO7Xw4_jWlfVYCaRPCWpkYzkymH1CSNtU24KUvNhS1tFJdJGiVcC6tiy60pUy60jhQerWB5bMpIuQTHvQN3Ux8y6l0F2cFC8iP3lsG6KgVFvSLrg3SiJN9scKP0nnLMO0Ig7afs743wGru9ZpkNG97uo__tU63Aw55ak51uLTyGJVc9gdWdSrX12Zy8J8HZNVgRVmH8zTUhDI3YeaXOTkxDZg6X4aXzJ6ZLWkWCH39fEKwhbU189k_sY0IpjIDpp_D9Vt7pGSxXdeXWgHBU6VmOUi3GD25yo3zipIgpg8TDSCtGEA8zXJg-47ov_HFaBMt_khcdKgpERRFQUbARfFj0Oe_yjdzYen1AQNHLnqa4mv4RvFlcRqnhTUGqcvWFb5PhYkTdE9s87wC3uF3iSWgq8xF8HBB4Nfi_n-XFzc_yGu6PDw8mxWRvuv8SHjDkip3z-zost7MLtwH3zGV70sxehTVF4Pi2kfkHWVFdNg
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VLUJceJXHQgEjARewNnHiOD4gVGhXrVqtVhWg3oxjO1IlmpRNWrR_jV_H2Em2QhW99cAlihQncezP428yL4DXWkhZFImkRZZZmtqopJrnMS25EKgQWZ6G2KpvB2I2y4-O5HwNfg-xMN6tcpCJQVDb2vh_5BOGPCVETspJ2btFzLenH09_Ul9Byltah3IaHUT23fIXqm_Nh71tnOs3jE13vnzepX2FAWoSwVuamoKZTDukKWlc2ISbsiy4sKWN4jJJo4QXwurYcmvKlIuiiDQerWB5bMpIuwSfewPWBZKMdATrn3Zm88PVPoBMXAZbqxQUtYysD9mJknzS4Lbp_eaYd4tAJYCyv7fFS1z3kp02bH_Tu__zwN2DOz3pJlvdKrkPa656ABtblW7rkyV5S4IbbLAvbMDuoWtCgBqxy0qfHJuGLBwu0HPnT0yXzooED_--VFhD2pr4vKB4jwlFMgLaH8LXa_mmRzCq6so9AcJR2Wc5yrsYB9_kRvuUShHTBimJkVaMIR5mW5k-F7svCfJDBZ-AJFcdQhQiRAWEKDaGd6t7TrtMJFe23hzQoHqp1KgLKIzh1eoyyhNvJNKVq898mwyXKWql2OZxB77V6xJPT1OZj-H9gMaLh_-7L0-v7stLuIWAVAd7s_1ncJshiey84jdh1C7O3HO4ac7b42bxol9gBL5fNzT_AHIxZ1A
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Residual+dynamics+resolves+recurrent+contributions+to+neural+computation&rft.jtitle=Nature+neuroscience&rft.au=Galgali%2C+Aniruddh+R&rft.au=Sahani%2C+Maneesh&rft.au=Mante%2C+Valerio&rft.date=2023-02-01&rft.eissn=1546-1726&rft.volume=26&rft.issue=2&rft.spage=326&rft_id=info:doi/10.1038%2Fs41593-022-01230-2&rft_id=info%3Apmid%2F36635498&rft.externalDocID=36635498
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1097-6256&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1097-6256&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1097-6256&client=summon