The road to fully programmable protein catalysis

The ability to design efficient enzymes from scratch would have a profound effect on chemistry, biotechnology and medicine. Rapid progress in protein engineering over the past decade makes us optimistic that this ambition is within reach. The development of artificial enzymes containing metal cofact...

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Veröffentlicht in:	Nature (London) Jg. 606; H. 7912; S. 49 - 58
Hauptverfasser:	Lovelock, Sarah L., Crawshaw, Rebecca, Basler, Sophie, Levy, Colin, Baker, David, Hilvert, Donald, Green, Anthony P.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 02.06.2022 Nature Publishing Group
Schlagworte:	119/118 631/92/606 639/638/77/603 Binding sites Biocatalysis Biocatalysts Biotechnology Biotechnology - methods Biotechnology - trends Catalysis Catalysts Cofactors Computer applications Deep learning Design Engineering Enzymes Humanities and Social Sciences Laboratories Ligands multidisciplinary Protein engineering Protein Engineering - methods Protein Engineering - trends Protein structure Proteins Proteins - chemistry Proteins - metabolism Review Article Robust design Science Science (multidisciplinary) Structural analysis Zinc
ISSN:	0028-0836, 1476-4687, 1476-4687
Online-Zugang:	Volltext
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