The pathophysiology of sepsis and precision-medicine-based immunotherapy

Sepsis remains a major cause of morbidity and mortality in both low- and high-income countries. Antibiotic therapy and supportive care have significantly improved survival following sepsis in the twentieth century, but further progress has been challenging. Immunotherapy trials for sepsis, mainly ai...

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Bibliographic Details
Published in:	Nature immunology Vol. 25; no. 1; pp. 19 - 28
Main Authors:	Giamarellos-Bourboulis, Evangelos J., Aschenbrenner, Anna C., Bauer, Michael, Bock, Christoph, Calandra, Thierry, Gat-Viks, Irit, Kyriazopoulou, Evdoxia, Lupse, Mihaela, Monneret, Guillaume, Pickkers, Peter, Schultze, Joachim L., van der Poll, Tom, van de Veerdonk, Frank L., Vlaar, Alexander P. J., Weis, Sebastian, Wiersinga, W. Joost, Netea, Mihai G.
Format:	Journal Article
Language:	English
Published:	New York Nature Publishing Group US 01.01.2024 Nature Publishing Group
Subjects:	631/250/254 692/699/255/1318 Antibiotics Biomarkers Biomedical and Life Sciences Biomedicine Clinical trials Heterogeneity Humans Immune response Immunology Immunotherapy Infectious Diseases Molecular modelling Morbidity Pathophysiology Precision Medicine Review Article Sepsis Sepsis - therapy
ISSN:	1529-2908, 1529-2916, 1529-2916
Online Access:	Get full text
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