Cytokine BAFF released by Helicobacter pylori-infected macrophages triggers the Th17 response in human chronic gastritis

BAFF is a crucial cytokine that affects the activity of both innate and adaptive immune cells. It promotes the expansion of Th17 cells in autoimmune disorders. With this study, we investigated the BAFF/Th17 responses in Helicobacter pylori-induced gastritis in humans. Our results show that the mucos...

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Veröffentlicht in:	The Journal of immunology (1950) Jg. 193; H. 11; S. 5584
Hauptverfasser:	Munari, Fabio, Fassan, Matteo, Capitani, Nagaja, Codolo, Gaia, Vila-Caballer, Marian, Pizzi, Marco, Rugge, Massimo, Della Bella, Chiara, Troilo, Arianna, D'Elios, Sofia, Baldari, Cosima T, D'Elios, Mario M, de Bernard, Marina
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.12.2014
Schlagworte:	Adaptive Immunity B-Cell Activating Factor - metabolism Cell Differentiation Cells, Cultured Chronic Disease Gastritis - etiology Gastritis - immunology Helicobacter Infections - complications Helicobacter Infections - immunology Helicobacter pylori - immunology Humans Immunity, Innate Interleukin-17 - metabolism Macrophages - immunology Macrophages - microbiology Mucous Membrane - immunology Mucous Membrane - microbiology Reactive Oxygen Species - metabolism Th17 Cells - immunology
ISSN:	1550-6606, 1550-6606
Online-Zugang:	Weitere Angaben
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