Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials

Fragile X syndrome (FXS), the most common cause of inherited intellectual disability and autistic spectrum disorder, is typically caused by transcriptional silencing of the X-linked FMR1 gene. Work in animal models has described altered synaptic plasticity, a result of the up-regulation of metabotro...

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