Cell‐Free Extracts from Human Fat Tissue with a Hyaluronan‐Based Hydrogel Attenuate Inflammation in a Spinal Cord Injury Model through M2 Microglia/Microphage Polarization

Treatment for spinal cord injuries (SCIs) is often ineffective because SCIs result in a loss of nerve tissue, glial scar formation, local ischemia and secondary inflammation. The current promising strategy for SCI is the combination of bioactive materials and cytokines. Bioactive materials support t...

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Bibliographic Details
Published in:	Small (Weinheim an der Bergstrasse, Germany) Vol. 18; no. 17; pp. e2107838 - n/a
Main Authors:	Xu, Guang‐Yu, Xu, Shun, Zhang, Yu‐Xuan, Yu, Zi‐You, Zou, Fei, Ma, Xiao‐Sheng, Xia, Xin‐Lei, Zhang, Wen‐Jie, Jiang, Jian‐Yuan, Song, Jian
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 01.04.2022
Subjects:	Animals Biocompatibility Biological activity Biomedical materials Cell Extracts Cytokines Cytokines - metabolism fat extract Genotype & phenotype Humans Hyaluronic acid Hyaluronic Acid - pharmacology Hydrogels Inflammation - drug therapy Inflammation - metabolism Injury prevention M2 polarization Macrophages Mice Microglia Nanotechnology Polarization Spinal cord Spinal cord injuries Spinal Cord Injuries - drug therapy STAT6 STAT6 M2 polarization spinal cord injuries fat extract
ISSN:	1613-6810, 1613-6829, 1613-6829
Online Access:	Get full text
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