Salivary Proteome Profile of Xerostomic Patients Reveals Pathway Dysregulation Related to Neurodegenerative Diseases: A Pilot Study

Xerostomia, the subjective complaint of a dry mouth, is frequently associated with salivary flow reduction and/or salivary gland hypofunction. This condition significantly impacts an individual’s quality of life and oral health, including difficulties in speaking, chewing, and swallowing. Xerostomia...

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Bibliographic Details
Published in:	International journal of molecular sciences Vol. 26; no. 15; p. 7037
Main Authors:	Henry, Abhijeet A., Beckman, Micaela F., Fry, Thomas S., Brennan, Michael T., Bahrani Mougeot, Farah, Mougeot, Jean-Luc C.
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 22.07.2025 MDPI
Subjects:	Adult Aged Alzheimer's disease Amyotrophic lateral sclerosis Aquaporins Autoimmune diseases Disease Estrogens Exocrine glands Female Genes Hormone replacement therapy Humans Lubricants & lubrication Male Middle Aged Neurodegeneration Neurodegenerative Diseases - metabolism Older people Oxidative stress Pacemakers Parkinson's disease Pilot Projects Protein Interaction Maps Proteins Proteome - metabolism Proteomics - methods Saliva - metabolism Salivary Glands - metabolism Salivary Proteins and Peptides - metabolism Xerostomia - metabolism dry mouth saliva neurodegenerative diseases xerostomia proteomics salivary hypofunction
ISSN:	1422-0067, 1661-6596, 1422-0067
Online Access:	Get full text
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