Characterization and therapeutic strategies for refractory vulvar lichen sclerosus: an 8-year single-center retrospective study and current evidence synthesis

Untreated vulvar lichen sclerosus (VLS) can lead to irreversible anatomical changes and increase malignancy risk. Some patients show poor response to standard treatments, resulting in refractory cases (RVLS). To explore risk factors associated with RVLS and integrate treatment strategies for improve...

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Bibliographic Details
Published in:	The Journal of dermatological treatment Vol. 36; no. 1; p. 2531140
Main Authors:	Liu, Lin, Cui, Jun, Sun, Kailv, Yang, Min, Zhang, Qiuli, Yang, Kun, Jianmin, Chang
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis Group 01.12.2025
Subjects:	Adult Aged Cyclosporine - therapeutic use Female Humans Janus Kinase Inhibitors - therapeutic use Lichen sclerosus Middle Aged Recurrence refractory lichen sclerosus Retrospective Studies Risk Factors Treatment Outcome vulvar disease Vulvar Lichen Sclerosus - diagnosis Vulvar Lichen Sclerosus - therapy vulvar disease Lichen sclerosus refractory lichen sclerosus
ISSN:	0954-6634, 1471-1753, 1471-1753
Online Access:	Get full text
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