Intrachiasmatic abscess caused by IgG4-related hypophysitis

Introduction Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported. Methods In this study, we report a case of a 29-year-old female with bite...

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Bibliographic Details
Published in:Acta neurochirurgica Vol. 159; no. 11; pp. 2229 - 2233
Main Authors: Hadjigeorgiou, Georgios F., Lund, Eva Løbner, Poulsgaard, Lars, Feldt-Rasmussen, Ulla, Rasmussen, Åse Krogh, Wegener, Marianne, Fugleholm, Kåre
Format: Journal Article
Language:English
Published: Vienna Springer Vienna 01.11.2017
Springer Nature B.V
Subjects:
Adult
Autoimmune Hypophysitis - complications
Autoimmune Hypophysitis - diagnostic imaging
Autoimmune Hypophysitis - pathology
Autoimmune Hypophysitis - surgery
Brain Abscess - complications
Brain Abscess - diagnostic imaging
Brain Abscess - pathology
Brain Abscess - surgery
Case Report - Brain Tumors
Case reports
Compression
Decompression
Decompression, Surgical
Female
Hemianopsia - etiology
Humans
Immunoglobulin G
Interventional Radiology
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Minimally Invasive Surgery
Neurology
Neuroradiology
Neurosurgery
Neurosurgical Procedures
Optic chiasm
Optic Chiasm - diagnostic imaging
Optic Chiasm - surgery
Pituitary
Rare diseases
Surgical Orthopedics
Vision
IgG4
Intrachiasmatic
Abscess
Hypophysitis
ISSN:0001-6268, 0942-0940, 0942-0940
Online Access:Get full text
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Summary:Introduction Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported. Methods In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess. Results The histologic findings were consistent with IgG4 hypophysitis. Conclusion This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.
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ISSN:0001-6268
0942-0940
0942-0940
DOI:10.1007/s00701-017-3288-8