Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency

Nuclear reprogramming efficiency has been shown to be highly variable among different types of somatic cells and different individuals, yet the underlying mechanism remains largely unknown. Several studies have shown that reprogramming of fibroblasts into induced pluripotent stem cells (iPSCs) requi...

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Vydáno v:	Stem cells and development Ročník 26; číslo 3; s. 166
Hlavní autoři:	Zhou, Yan, Al-Saaidi, Rasha Abdelkadhem, Fernandez-Guerra, Paula, Freude, Kristine K, Olsen, Rikke Katrine Jentoft, Jensen, Uffe Birk, Gregersen, Niels, Hyttel, Poul, Bolund, Lars, Aagaard, Lars, Bross, Peter, Luo, Yonglun
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.02.2017
Témata:	Adolescent Cell Respiration Cellular Reprogramming Child Child, Preschool Dermis - cytology Energy Metabolism Female Fibroblasts - metabolism Gene Editing Humans Induced Pluripotent Stem Cells - cytology Induced Pluripotent Stem Cells - metabolism Infant, Newborn Male Middle Aged Mitochondria - metabolism Reproducibility of Results nuclear reprogramming induced pluripotent stem cells mitochondrial spare respiratory capacity reprogramming efficiency oxidative phosphorylation
ISSN:	1557-8534, 1557-8534
On-line přístup:	Zjistit podrobnosti o přístupu
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