Unravelling the Antiproliferative Activity of 1,2,5-oxadiazole Derivatives

To develop several new derivatives aimed to complete the studies concerning the antiproliferative profile of the oxadiazole derivative MD77. The substitution pattern around the phenyl rings of this compound was analyzed through the synthesis of positional isomers and of analogues bearing different s...

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Bibliographic Details
Published in:	Anticancer research Vol. 39; no. 7; pp. 3453 - 3461
Main Authors:	EHRSAM, DANIEL, PORTA, FABIOLA, MORI, MATTEO, SCHWABEDISSEN, HENRIETTE E. MEYER ZU, DALLA VIA, LISA, GARCIA-ARGAEZ, AÌDA NELLY, BASILE, LIVIA, MENEGHETTI, FIORELLA, VILLA, STEFANIA, GELAIN, ARIANNA
Format:	Journal Article
Language:	English
Published:	Greece International Institute of Anticancer Research 01.07.2019
Subjects:	Antineoplastic Agents - pharmacology Antiproliferatives Cancer Cell Line, Tumor Cell Proliferation - drug effects Chloride Chromatography DNA topoisomerase (ATP-hydrolysing) Humans Isomers Oxadiazoles Oxadiazoles - pharmacology Tumor cell lines United States > US HeLa MDA-MB 468 topoisomerase II MCF-7 HCT-116 cytotoxicity Furazane
ISSN:	0250-7005, 1791-7530, 1791-7530
Online Access:	Get full text
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