Multiple Sequence Alignment as a Facility-Location Problem

A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MA...

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Bibliographic Details

Published in:	INFORMS journal on computing Vol. 16; no. 4; pp. 430 - 440
Main Authors:	Just, Winfried, Vedova, Gianluca Della
Format:	Journal Article
Language:	English
Published:	Linthicum INFORMS 01.11.2004 Institute for Operations Research and the Management Sciences
Subjects:	Algorithms analysis of algorithms: computational complexity Computer science Correlation analysis facilities-equipment planning: location Studies
ISSN:	1091-9856, 1526-5528, 1091-9856
Online Access:	Get full text
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