The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education

NK cells play an important role in the defense against viral infections. However, little is known about the regulation of NK cell responses during the first days of acute viral infections in humans. In this study, we used the live attenuated yellow fever virus (YFV) vaccine 17D as a human in vivo mo...

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Vydáno v:	The Journal of immunology (1950) Ročník 195; číslo 7; s. 3262
Hlavní autoři:	Marquardt, Nicole, Ivarsson, Martin A, Blom, Kim, Gonzalez, Veronica D, Braun, Monika, Falconer, Karolin, Gustafsson, Rasmus, Fogdell-Hahn, Anna, Sandberg, Johan K, Michaëlsson, Jakob
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.10.2015
Témata:	Adult Antibodies, Neutralizing - immunology Antigens, CD - biosynthesis Antigens, Differentiation, T-Lymphocyte - biosynthesis B-Lymphocytes - immunology CD57 Antigens - metabolism Cell Differentiation - immunology Cell Proliferation Histocompatibility Antigens Class I - immunology Humans Interferon Type I - blood Interferon Type I - immunology Interleukin-12 Subunit p35 - immunology Interleukin-18 - immunology K562 Cells Ki-67 Antigen - biosynthesis Killer Cells, Natural - cytology Killer Cells, Natural - immunology Lectins, C-Type - biosynthesis Lymphocyte Activation - immunology Middle Aged Receptors, KIR - immunology T-Lymphocytes - immunology Vaccines, Attenuated - immunology Viral Load - immunology Viral Vaccines - immunology Yellow Fever Vaccine - immunology Yellow fever virus - immunology
ISSN:	1550-6606, 1550-6606
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