Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing

A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false...

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Veröffentlicht in:Chemical communications (Cambridge, England) Jg. 55; H. 12; S. 1742
Hauptverfasser: Song, Yongchao, Xu, Tailin, Xu, Li-Ping, Zhang, Xueji
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England 05.02.2019
Schlagworte:
Biosensing Techniques
Electrochemical Techniques
Ferrous Compounds - chemistry
Gold - chemistry
Graphite - chemistry
Humans
Metallocenes - chemistry
MicroRNAs - analysis
Nanostructures - chemistry
Spectrum Analysis, Raman
ISSN:1364-548X, 1364-548X
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Zusammenfassung:A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
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content type line 23
ISSN:1364-548X
1364-548X
DOI:10.1039/c8cc09586h