Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing

A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false...

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Vydáno v:Chemical communications (Cambridge, England) Ročník 55; číslo 12; s. 1742
Hlavní autoři: Song, Yongchao, Xu, Tailin, Xu, Li-Ping, Zhang, Xueji
Médium: Journal Article
Jazyk:angličtina
Vydáno: England 05.02.2019
Témata:
Biosensing Techniques
Electrochemical Techniques
Ferrous Compounds - chemistry
Gold - chemistry
Graphite - chemistry
Humans
Metallocenes - chemistry
MicroRNAs - analysis
Nanostructures - chemistry
Spectrum Analysis, Raman
ISSN:1364-548X, 1364-548X
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Abstract A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.
AbstractList A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.
A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has been developed. The biosensor was used to successfully perform tri-modal quantitative trace miRNA-375 detection, which enormously reduces false positive readings caused by interference and ambiguous signals, and has significant implications for use in precise physiological and pathological diagnosis.
Author Song, Yongchao
Zhang, Xueji
Xu, Li-Ping
Xu, Tailin
Author_xml – sequence: 1
  givenname: Yongchao
  surname: Song
  fullname: Song, Yongchao
  email: xutailin@ustb.edu.cn, xuliping@ustb.edu.cn, zhangxueji@ustb.edu.cn
  organization: Research Center for Bioengineering and Sensing Technology, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, P. R. China. xutailin@ustb.edu.cn xuliping@ustb.edu.cn zhangxueji@ustb.edu.cn
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  givenname: Tailin
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  fullname: Xu, Tailin
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  givenname: Li-Ping
  surname: Xu
  fullname: Xu, Li-Ping
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  givenname: Xueji
  surname: Zhang
  fullname: Zhang, Xueji
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Snippet A nanodendritic gold/graphene-based biosensor that can perform fluorescence, SERS and electrochemical tri-modal miRNA detection in a single microdroplet has...
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SubjectTerms Biosensing Techniques
Electrochemical Techniques
Ferrous Compounds - chemistry
Gold - chemistry
Graphite - chemistry
Humans
Metallocenes - chemistry
MicroRNAs - analysis
Nanostructures - chemistry
Spectrum Analysis, Raman
Title Nanodendritic gold/graphene-based biosensor for tri-mode miRNA sensing
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