Reoviruses hijack the SMARCB1-MYC transcriptional regulation complex to activate autophagy for persistent viral infection in leafhopper vector

Autophagy plays a crucial role in virus-host interactions, as viral components and particles can be degraded by the host’s autophagic machinery. Additionally, some viruses can hijack autophagy for their own benefit. However, the mechanisms underlying the transcriptional regulation of autophagy by ar...

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Bibliographic Details

Published in:	PLoS pathogens Vol. 21; no. 10; p. e1013569
Main Authors:	Wang, Hui, Liu, Runfa, Xiao, Guangming, Li, Yanan, Li, Bozhong, Chen, Qian, Wei, Taiyun
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science (PLoS) 01.10.2025
Subjects:	Animals Autophagy - physiology Hemiptera - metabolism Hemiptera - virology Insect Vectors - virology Plant Diseases - virology Proto-Oncogene Proteins c-myc - genetics Proto-Oncogene Proteins c-myc - metabolism Reoviridae - pathogenicity Reoviridae - physiology SMARCB1 Protein - genetics SMARCB1 Protein - metabolism
ISSN:	1553-7374, 1553-7366, 1553-7374
Online Access:	Get full text
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