Immunophenotypic changes in the tumor and tumor microenvironment during progression to multiple myeloma

Investigation of the cellular and molecular mechanisms of disease progression from precursor plasma cell disorders to active disease increases our understanding of multiple myeloma (MM) pathogenesis and supports the development of novel therapeutic strategies. In this analysis, single-cell RNA seque...

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Veröffentlicht in:	PLoS genetics Jg. 21; H. 10; S. e1011848
Hauptverfasser:	Bergiers, Isabelle, Köse, Murat Cem, Skerget, Sheri, Malfait, Milan, Fourneau, Nele, Ellis, Jenna-Claire, Vanhoof, Greet, Smets, Tina, Verbist, Bie, De Maeyer, Dries, Van Houdt, Jeroen, Van der Borght, Koen, Verona, Raluca, Heidrich, Bradley, Kurth, William, Delforge, Michel, Meuleman, Nathalie, Van Droogenbroeck, Jan, Vlummens, Philip, Heuck, Christoph J., Beguin, Yves, Bahlis, Nizar, Casneuf, Tineke, Caers, Jo
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science (PLoS) 01.10.2025
Schlagworte:	Aged CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - pathology Disease Progression Female Humans Immunophenotyping Macrophages - immunology Male Middle Aged Monoclonal Gammopathy of Undetermined Significance - genetics Monoclonal Gammopathy of Undetermined Significance - immunology Monoclonal Gammopathy of Undetermined Significance - pathology Multiple Myeloma - genetics Multiple Myeloma - immunology Multiple Myeloma - pathology Smoldering Multiple Myeloma - genetics Smoldering Multiple Myeloma - immunology Smoldering Multiple Myeloma - pathology Tumor Microenvironment - genetics Tumor Microenvironment - immunology
ISSN:	1553-7404, 1553-7390, 1553-7404
Online-Zugang:	Volltext
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