The Fanconi anaemia pathway: new players and new functions

Key Points The Fanconi anaemia pathway comprises 19 Fanconi anaemia proteins (FANCA to FANCT) and many associated proteins. Germline inactivation of any of the Fanconi anaemia genes causes the disease Fanconi anaemia, which is a genetic disorder characterized by bone marrow failure and predispositio...

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Veröffentlicht in:	Nature reviews. Molecular cell biology Jg. 17; H. 6; S. 337 - 349
Hauptverfasser:	Ceccaldi, Raphael, Sarangi, Prabha, D'Andrea, Alan D.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 01.06.2016 Nature Publishing Group
Schlagworte:	631/337/1427 631/337/151 631/337/641 631/80/304 Analysis Anemia Animals Biochemistry Bone marrow Cancer Research Cell Biology Cell cycle Deoxyribonucleic acid Developmental Biology DNA DNA Damage DNA Repair DNA Replication Fanconi Anemia - genetics Fanconi Anemia Complementation Group Proteins - physiology Fanconi's anemia Fibroblasts Genes Genomes Humans Life Sciences Ovarian cancer Proteins review-article Stem Cells
ISSN:	1471-0072, 1471-0080
Online-Zugang:	Volltext
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