Pediatric multiple sclerosis
Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are...
Saved in:
| Published in: | Current neurology and neuroscience reports Vol. 8; no. 5; pp. 434 - 441 |
|---|---|
| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
New York
Current Science Inc
01.09.2008
Springer Nature B.V |
| Subjects: | |
| ISSN: | 1528-4042, 1534-6293, 1534-6293 |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are less likely to have spinal cord symptoms than adults. They mostly experience a relapsing-remitting course. Their initial brain MRI shows more frequent involvement of the posterior fossa, less well-defined ovoid lesions, and more confluent lesions that decrease over time in patients with prepubertal onset, making early diagnosis even more difficult. Although disability progression is slower than in adults, pediatric onset MS leads to significant disability at a younger age and may be worse in non-white patients (up to 50% in North America). The rareness of pediatric-onset MS has precluded enrollment in clinical trials. Thus, children are receiving off-label adult therapies without clear evidence of their effectiveness and limited knowledge of their tolerability. |
|---|---|
| AbstractList | Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are less likely to have spinal cord symptoms than adults. They mostly experience a relapsing-remitting course. Their initial brain MRI shows more frequent involvement of the posterior fossa, less well-defined ovoid lesions, and more confluent lesions that decrease over time in patients with prepubertal onset, making early diagnosis even more difficult. Although disability progression is slower than in adults, pediatric onset MS leads to significant disability at a younger age and may be worse in non-white patients (up to 50% in North America). The rareness of pediatric-onset MS has precluded enrollment in clinical trials. Thus, children are receiving off-label adult therapies without clear evidence of their effectiveness and limited knowledge of their tolerability. Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are less likely to have spinal cord symptoms than adults. They mostly experience a relapsing-remitting course. Their initial brain MRI shows more frequent involvement of the posterior fossa, less well-defined ovoid lesions, and more confluent lesions that decrease over time in patients with prepubertal onset, making early diagnosis even more difficult. Although disability progression is slower than in adults, pediatric onset MS leads to significant disability at a younger age and may be worse in non-white patients (up to 50% in North America). The rareness of pediatric-onset MS has precluded enrollment in clinical trials. Thus, children are receiving off-label adult therapies without clear evidence of their effectiveness and limited knowledge of their tolerability.Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are less likely to have spinal cord symptoms than adults. They mostly experience a relapsing-remitting course. Their initial brain MRI shows more frequent involvement of the posterior fossa, less well-defined ovoid lesions, and more confluent lesions that decrease over time in patients with prepubertal onset, making early diagnosis even more difficult. Although disability progression is slower than in adults, pediatric onset MS leads to significant disability at a younger age and may be worse in non-white patients (up to 50% in North America). The rareness of pediatric-onset MS has precluded enrollment in clinical trials. Thus, children are receiving off-label adult therapies without clear evidence of their effectiveness and limited knowledge of their tolerability. Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated encephalomyelitis. Pediatric-onset MS patients are more likely to be male, have seizures, and have brainstem and cerebellar symptoms than adults, and are less likely to have spinal cord symptoms than adults. They mostly experience a relapsing-remitting course. Their initial brain MRI shows more frequent involvement of the posterior fossa, less well-defined ovoid lesions, and more confluent lesions that decrease over time in patients with prepubertal onset, making early diagnosis even more difficult. Although disability progression is slower than in adults, pediatric onset MS leads to significant disability at a younger age and may be worse in non-white patients (up to 50% in North America). The rareness of pediatric-onset MS has precluded enrollment in clinical trials. Thus, children are receiving off-label adult therapies without clear evidence of their effectiveness and limited knowledge of their tolerability.[PUBLICATION ABSTRACT] |
| Author | Chabas, Dorothee Strober, Jonathan Waubant, Emmanuelle |
| Author_xml | – sequence: 1 givenname: Dorothee surname: Chabas fullname: Chabas, Dorothee email: dorothee.chabas@ucsf.edu organization: Regional Pediatric Multiple Sclerosis Center, University of California, San Francisco – sequence: 2 givenname: Jonathan surname: Strober fullname: Strober, Jonathan – sequence: 3 givenname: Emmanuelle surname: Waubant fullname: Waubant, Emmanuelle |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/18713581$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kEtLAzEQx4NU7EM_gCBSPHhbTTbvoxRfUNCDnkOSzUrKPmqye_DbN8tWhYIehpnD7zfM_Odg0rSNA-AcwRsEIb-NCEkEMwhFKsYzdARmiGKSsVziyTDnIiOQ5FMwj3EDYZ4seQKmSHCEqUAzcPHqCq-74O2y7qvObyu3jLZyoY0-noLjUlfRne37Arw_3L-tnrL1y-Pz6m6dWcxkl1nGHTQYcy14mXOBiIEFk7QokaHUaOyIJAbbUkucG00MdUwbgyk0urTY4AW4HvduQ_vZu9ip2kfrqko3ru2jYpIQIoVM4NUBuGn70KTblOCScQw5TtDlHupN7Qq1Db7W4Ut9P50APgI2fRmDK5X1ne5823RB-0ohqIZ41RivSvGqIV41mOjA_Fn-j5OPTkxs8-HC781_SzvGPYor |
| CitedBy_id | crossref_primary_10_1038_nrneurol_2010_198 crossref_primary_10_1080_09297049_2012_748888 crossref_primary_10_3389_fneur_2024_1359938 crossref_primary_10_1002_ana_24364 crossref_primary_10_1016_j_pediatrneurol_2009_04_018 crossref_primary_10_1016_S0028_3843_14_60027_X crossref_primary_10_1177_1352458515586088 crossref_primary_10_1007_s00276_009_0560_5 crossref_primary_10_1016_j_jns_2015_04_025 crossref_primary_10_1586_ern_12_101 crossref_primary_10_1002_hbm_22148 crossref_primary_10_1007_s11940_009_0024_6 crossref_primary_10_1097_NEN_0000000000000214 crossref_primary_10_3109_09540261003589588 crossref_primary_10_3390_children12050631 crossref_primary_10_4274_jmsr_galenos_2023_2023_9_2 crossref_primary_10_1093_brain_awp278 crossref_primary_10_1111_cen3_12347 crossref_primary_10_1177_1352458516652497 crossref_primary_10_4329_wjr_v8_i1_1 |
| Cites_doi | 10.1002/ana.21244 10.1177/0961203307080636 10.1007/s10072-004-0334-0 10.1212/01.wnl.0000259407.40023.ab 10.1186/1471-2172-7-2 10.1038/sj.ijo.0802328 10.1016/S1474-4422(07)70196-5 10.1191/1352458503ms909oa 10.1073/pnas.0707731105 10.1111/j.1600-0404.1992.tb05086.x 10.1016/S0022-3476(87)80454-7 10.1001/archneur.59.6.1006 10.1007/s10072-004-0346-9 10.1016/S0022-3476(98)70371-3 10.1212/01.wnl.0000268266.50850.48 10.1086/504326 10.1093/brain/awm198 10.1001/archpedi.161.12.1176 10.1001/archneur.63.3.390 10.1002/ana.1032 10.1016/j.jneuroim.2007.08.005 10.1212/01.wnl.0000259422.44235.a8 10.1093/brain/awl368 10.1007/s004150170205 10.1093/brain/awg081 10.1002/ana.21322 10.1212/01.wnl.0000208505.81912.82 10.1056/NEJMoa067597 10.1016/j.cca.2006.06.017 10.1212/WNL.53.3.478 10.1172/JCI200316721 10.1212/01.wnl.0000326896.66714.ae 10.1212/WNL.59.7.1006 10.1080/87565640701375872 10.1038/nm1715 10.1212/01.WNL.0000145762.60562.5D 10.1212/01.WNL.0000113723.36715.A6 10.1212/01.WNL.0000036907.37650.8E 10.1212/01.WNL.0000144352.67102.BC |
| ContentType | Journal Article |
| Copyright | Current Medicine Group LLC 2008 |
| Copyright_xml | – notice: Current Medicine Group LLC 2008 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7TK 7X7 7XB 88E 88G 8AO 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH GNUQQ K9. M0S M1P M2M PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 |
| DOI | 10.1007/s11910-008-0067-1 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Neurosciences Abstracts ProQuest Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest Pharma Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Psychology Database ProQuest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Neurosciences Abstracts ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic ProQuest One Psychology |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1534-6293 |
| EndPage | 441 |
| ExternalDocumentID | 2410011981 18713581 10_1007_s11910_008_0067_1 |
| Genre | Journal Article Review |
| GroupedDBID | --- -5E -5G -BR -EM -Y2 -~C .86 .VR 06C 06D 0R~ 0VY 1N0 203 29F 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2~H 30V 3V. 4.4 406 408 40D 40E 53G 5GY 5VS 6NX 7X7 875 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABDZT ABECU ABFTV ABHQN ABIPD ABJNI ABJOX ABKCH ABMNI ABMQK ABNWP ABPLI ABQBU ABSXP ABTEG ABTKH ABTMW ABUWG ABWNU ABXPI ACAOD ACDTI ACGFS ACHSB ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACREN ACSNA ACZOJ ADBBV ADHHG ADHIR ADINQ ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADYOE ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFKRA AFLOW AFQWF AFWTZ AFYQB AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMTXH AMXSW AMYLF AMYQR AOCGG ARMRJ AXYYD AZQEC B-. BA0 BDATZ BENPR BGNMA BPHCQ BVXVI C1A CAG CCPQU COF CS3 CSCUP CUW DDRTE DNIVK DPUIP DU5 DWQXO EBD EBLON EBS EIOEI EJD EMOBN ESBYG F5P FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 H13 HF~ HG6 HMCUK HMJXF HRMNR HZ~ IJ- IKXTQ IMOTQ IWAJR IXC IXD IXE I~Z J-C JBSCW JZLTJ KOV LLZTM M1P M2M M4Y MA- N9A NPVJJ NQJWS NU0 O9- O9J OVD P9S PF0 PQQKQ PROAC PSQYO PSYQQ PT4 Q2X QOR QOS R89 R9I ROL RPX RSV S16 S1Z S27 S37 S3B SAP SDH SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 TEORI TSG TSK TSV TUC U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W48 WH7 WK8 YLTOR Z7U Z7W Z82 Z87 ZMTXR ZOVNA ~A9 AAPKM AAYXX ABBRH ABDBE ABFSG ABRTQ ACSTC AEZWR AFDZB AFFHD AFHIU AFOHR AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT PJZUB PPXIY CGR CUY CVF ECM EIF NPM 7TK 7XB 8FK K9. PKEHL PQEST PQUKI PRINS Q9U 7X8 |
| ID | FETCH-LOGICAL-c369t-c67e0b337a87f27814b0d695df1b55ba3e494b3cfa932ba4b5e6abb350bafc3b3 |
| IEDL.DBID | 7X7 |
| ISICitedReferencesCount | 21 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000258914200011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1528-4042 1534-6293 |
| IngestDate | Sun Nov 09 13:34:10 EST 2025 Wed Nov 26 13:11:45 EST 2025 Wed Feb 19 01:51:58 EST 2025 Sat Nov 29 06:46:30 EST 2025 Tue Nov 18 21:32:33 EST 2025 Fri Feb 21 02:29:49 EST 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Multiple Sclerosis Optic Neuritis Clinically Isolate Syndrome Neuromyelitis Optica Multiple Sclerosis Patient |
| Language | English |
| License | http://www.springer.com/tdm |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c369t-c67e0b337a87f27814b0d695df1b55ba3e494b3cfa932ba4b5e6abb350bafc3b3 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| PMID | 18713581 |
| PQID | 879673073 |
| PQPubID | 326346 |
| PageCount | 8 |
| ParticipantIDs | proquest_miscellaneous_69444989 proquest_journals_879673073 pubmed_primary_18713581 crossref_citationtrail_10_1007_s11910_008_0067_1 crossref_primary_10_1007_s11910_008_0067_1 springer_journals_10_1007_s11910_008_0067_1 |
| PublicationCentury | 2000 |
| PublicationDate | 2008-09-01 |
| PublicationDateYYYYMMDD | 2008-09-01 |
| PublicationDate_xml | – month: 09 year: 2008 text: 2008-09-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States – name: Philadelphia |
| PublicationTitle | Current neurology and neuroscience reports |
| PublicationTitleAbbrev | Curr Neurol Neurosci Rep |
| PublicationTitleAlternate | Curr Neurol Neurosci Rep |
| PublicationYear | 2008 |
| Publisher | Current Science Inc Springer Nature B.V |
| Publisher_xml | – name: Current Science Inc – name: Springer Nature B.V |
| References | Pittock, Lennon, Krecke (CR5) 2006; 63 van Veen, Nielsen, Berkhof (CR45) 2007; 190 Chabas, Pesic, McCulloch (CR2) 2008; 70 Pohl, Rostasy, Reiber, Hanefeld (CR23) 2004; 63 Pohl, Waubant, Banwell (CR49) 2007; 68 CR32 CR31 Hahn, Shroff, Blaser, Banwell (CR21) 2004; 62 Duquette, Murray, Pleines (CR8) 1987; 111 Pinhas-Hamiel, Barak, Siev-Ner, Achiron (CR11) 1998; 132 CR4 Boster, Endress, Hreha (CR42) 2008; 70 Stoevring, Frederiksen, Christiansen (CR44) 2007; 375 Banwell, Krupp, Kennedy (CR7) 2007; 6 Cree, Khan, Bourdette (CR39) 2004; 63 Ghassemi, Antel, Narayanan (CR24) 2008; 63 Pluchinotta, Schiavo, Vittadello (CR27) 2007; 16 MacAllister, Christodoulou, Milazzo, Krupp (CR17) 2007; 32 CR41 Simone, Carrara, Tortorella (CR15) 2002; 59 Mowry, Gajofatto, Blasco (CR33) 2008; 70 DeLuca, Ramagopalan, Herrera (CR47) 2007; 104 Mikaeloff, Caridade, Assi (CR35) 2007; 130 Weatherby, Thomson, Pepper (CR46) 2001; 248 Renoux, Vukusic, Mikaeloff (CR6) 2007; 356 Mikaeloff, Caridade, Tardieu (CR36) 2007; 130 CR19 CR18 Ghezzi, Ruggieri, Trojano, Filippi (CR9) 2004; 25 Trojano, Paolicelli, Bellacosa (CR13) 2004; 25 CR16 Boiko, Vorobeychik, Paty (CR14) 2002; 59 Ruggieri, Polizzi, Pavone, Grimaldi (CR12) 1999; 53 Sindern, Haas, Stark, Wurster (CR10) 1992; 86 Confavreux, Vukusic, Adeleine (CR25) 2003; 126 Tenenbaum, Segura (CR3) 2008; 70 Kurtis, Friedman, Leenstra (CR28) 2006; 42 Marrie, Cutter, Tyry (CR40) 2006; 66 Shalitin, Phillip (CR30) 2003; 27 Krupp, Banwell, Tenembaum (CR1) 2007; 68 Sanna, Di Giacomo, La Cava (CR29) 2003; 111 Krupp, McLinskey, Troell (CR43) 2008; 70 Lamason, Zhao, Rawat (CR26) 2006; 7 Banwell, Bar-Or, Cheung (CR48) 2008; 63 McDonald, Compston, Edan (CR20) 2001; 50 Mikaeloff, Caridade, Rossier (CR34) 2007; 161 CR22 Islam, Gauderman, Cozen, Mack (CR37) 2007; 69 Weinstock-Guttman, Jacobs, Brownscheidle (CR38) 2003; 9 R. Lamason (67_CR26) 2006; 7 T. Veen van (67_CR45) 2007; 190 D. Pohl (67_CR23) 2004; 63 R. Ghassemi (67_CR24) 2008; 63 T. Islam (67_CR37) 2007; 69 67_CR32 S.J. Weatherby (67_CR46) 2001; 248 P. Duquette (67_CR8) 1987; 111 C. Confavreux (67_CR25) 2003; 126 67_CR31 M. Trojano (67_CR13) 2004; 25 R.A. Marrie (67_CR40) 2006; 66 B. Banwell (67_CR48) 2008; 63 D. Chabas (67_CR2) 2008; 70 W.S. MacAllister (67_CR17) 2007; 32 V. Sanna (67_CR29) 2003; 111 D. Pohl (67_CR49) 2007; 68 S.N. Tenenbaum (67_CR3) 2008; 70 67_CR41 A. Ghezzi (67_CR9) 2004; 25 G.C. DeLuca (67_CR47) 2007; 104 M. Ruggieri (67_CR12) 1999; 53 B. Banwell (67_CR7) 2007; 6 O. Pinhas-Hamiel (67_CR11) 1998; 132 I.L. Simone (67_CR15) 2002; 59 B. Stoevring (67_CR44) 2007; 375 S.J. Pittock (67_CR5) 2006; 63 A. Boster (67_CR42) 2008; 70 A. Boiko (67_CR14) 2002; 59 67_CR19 Y. Mikaeloff (67_CR34) 2007; 161 67_CR18 Y. Mikaeloff (67_CR36) 2007; 130 67_CR16 L.B. Krupp (67_CR1) 2007; 68 E. Sindern (67_CR10) 1992; 86 F.R. Pluchinotta (67_CR27) 2007; 16 E.M. Mowry (67_CR33) 2008; 70 B. Weinstock-Guttman (67_CR38) 2003; 9 J.D. Kurtis (67_CR28) 2006; 42 Y. Mikaeloff (67_CR35) 2007; 130 67_CR22 B.A. Cree (67_CR39) 2004; 63 C. Renoux (67_CR6) 2007; 356 S. Shalitin (67_CR30) 2003; 27 W.I. McDonald (67_CR20) 2001; 50 C.D. Hahn (67_CR21) 2004; 62 L. Krupp (67_CR43) 2008; 70 67_CR4 15727226 - Neurol Sci. 2004 Nov;25 Suppl 4:S323-5 16636241 - Neurology. 2006 Apr 25;66(8):1235-40 18824673 - Neurology. 2008 Sep 30;71(14):1090-3 12499484 - Neurology. 2002 Dec 24;59(12):1922-8 3625402 - J Pediatr. 1987 Sep;111(3):359-63 17582070 - N Engl J Med. 2007 Jun 21;356(25):2603-13 16705573 - Clin Infect Dis. 2006 Jun 15;42(12):1692-8 15557527 - Neurology. 2004 Nov 23;63(10):1966-7 17931122 - Dev Neuropsychol. 2007;32(2):625-44 15596747 - Neurology. 2004 Dec 14;63(11):2039-45 17276994 - Brain. 2007 Apr;130(Pt 4):1105-10 17932975 - Ann Neurol. 2008 Jan;63(1):98-111 17827175 - Brain. 2007 Oct;130(Pt 10):2589-95 17438241 - Neurology. 2007 Apr 17;68(16 Suppl 2):S7-12 10449107 - Neurology. 1999 Aug 11;53(3):478-84 18056563 - Arch Pediatr Adolesc Med. 2007 Dec;161(12):1176-82 17438239 - Neurology. 2007 Apr 17;68(16 Suppl 2):S54-65 18087043 - Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20896-901 12370453 - Neurology. 2002 Oct 8;59(7):1006-10 15007138 - Neurology. 2004 Mar 9;62(5):806-8 12531880 - J Clin Invest. 2003 Jan;111(2):241-50 11374095 - J Neurol. 2001 Apr;248(4):304-10 15727231 - Neurol Sci. 2004 Nov;25 Suppl 4:S346-9 17010329 - Clin Chim Acta. 2007 Jan;375(1-2):57-62 18306242 - Ann Neurol. 2008 Mar;63(3):401-5 16533966 - Arch Neurol. 2006 Mar;63(3):390-6 1414248 - Acta Neurol Scand. 1992 Sep;86(3):280-4 9580781 - J Pediatr. 1998 Apr;132(4):735-7 17711887 - Lupus. 2007;16(8):550-5 12861226 - Int J Obes Relat Metab Disord. 2003 Aug;27(8):869-74 16504066 - BMC Immunol. 2006 Feb 22;7:2 11456302 - Ann Neurol. 2001 Jul;50(1):121-7 17646631 - Neurology. 2007 Jul 24;69(4):381-8 17884183 - J Neuroimmunol. 2007 Oct;190(1-2):157-64 12814178 - Mult Scler. 2003 Jun;9(3):293-8 17689148 - Lancet Neurol. 2007 Sep;6(9):773-81 12615637 - Brain. 2003 Apr;126(Pt 4):770-82 |
| References_xml | – ident: CR22 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: CR3 article-title: Presentation, course and outcome of multiple sclerosis in children under 10 years of age publication-title: Neurology – volume: 63 start-page: 98 year: 2008 end-page: 111 ident: CR48 article-title: Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes publication-title: Ann Neurol doi: 10.1002/ana.21244 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: CR43 article-title: Racial and ethnic findings in pediatric MS: an update publication-title: Neurology – ident: CR4 – volume: 16 start-page: 550 year: 2007 end-page: 555 ident: CR27 article-title: Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes publication-title: Lupus doi: 10.1177/0961203307080636 – volume: 25 start-page: S323 issue: Suppl4 year: 2004 end-page: S325 ident: CR13 article-title: Atypical for 15 ms of multiple sclerosis or different phases of a same disease? publication-title: Neurol Sci doi: 10.1007/s10072-004-0334-0 – ident: CR16 – volume: 68 start-page: S54 issue: 16Suppl2 year: 2007 end-page: S65 ident: CR49 article-title: Treatment of pediatric multiple sclerosis and variants publication-title: Neurology doi: 10.1212/01.wnl.0000259407.40023.ab – volume: 7 start-page: 2 year: 2006 ident: CR26 article-title: Sexual dimorphism in immune response genes as a function of puberty publication-title: BMC Immunol doi: 10.1186/1471-2172-7-2 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: CR42 article-title: Clinical spectrum of pediatric CNS demyelinating and related disorders at Children’s Hospital of Michigan, Detroit publication-title: Neurology – volume: 27 start-page: 869 year: 2003 end-page: 874 ident: CR30 article-title: Role of obesity and leptin in the pubertal process and pubertal growth—a review publication-title: Int J Obes Relat Metab Disord doi: 10.1038/sj.ijo.0802328 – volume: 6 start-page: 773 year: 2007 end-page: 781 ident: CR7 article-title: Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study publication-title: Lancet Neurol doi: 10.1016/S1474-4422(07)70196-5 – volume: 9 start-page: 293 year: 2003 end-page: 298 ident: CR38 article-title: Multiple sclerosis characteristics in African American patients in the New York State Multiple Sclerosis Consortium publication-title: Mult Scler doi: 10.1191/1352458503ms909oa – ident: CR19 – volume: 104 start-page: 20896 year: 2007 end-page: 20901 ident: CR47 article-title: An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0707731105 – volume: 86 start-page: 280 year: 1992 end-page: 284 ident: CR10 article-title: Early onset MS under the age of 16: clinical and paraclinical features publication-title: Acta Neurol Scand doi: 10.1111/j.1600-0404.1992.tb05086.x – volume: 111 start-page: 359 year: 1987 end-page: 363 ident: CR8 article-title: Multiple sclerosis in childhood: clinical profile in 125 patients publication-title: J Pediatr doi: 10.1016/S0022-3476(87)80454-7 – volume: 32 start-page: 625 year: 2007 end-page: 644 ident: CR17 article-title: Longitudinal neuropsychological assessment in pediatric multiple sclerosis publication-title: Dev Neuropsychol – volume: 59 start-page: 1006 year: 2002 end-page: 1010 ident: CR14 article-title: Early onset multiple sclerosis: a longitudinal study publication-title: Neurology doi: 10.1001/archneur.59.6.1006 – volume: 62 start-page: 806 year: 2004 end-page: 808 ident: CR21 article-title: MRI criteria for multiple sclerosis: evaluation in a pediatric cohort publication-title: Neurology – ident: CR32 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: CR33 article-title: Long lesions ion initial spinal cord MRI predict a final diagnosis of acute disseminated encephalomyelitis versus multiple sclerosis in children publication-title: Neurology – volume: 25 start-page: S346 issue: Suppl4 year: 2004 end-page: S349 ident: CR9 article-title: Italian studies on early-onset multiple sclerosis: the present and the future publication-title: Neurol Sci doi: 10.1007/s10072-004-0346-9 – volume: 63 start-page: 2039 year: 2004 end-page: 2045 ident: CR39 article-title: Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis publication-title: Neurology – volume: 53 start-page: 478 year: 1999 end-page: 484 ident: CR12 article-title: Multiple sclerosis in children under 6 years of age publication-title: Neurology – ident: CR18 – volume: 132 start-page: 735 year: 1998 end-page: 737 ident: CR11 article-title: Juvenile multiple sclerosis: clinical features and prognostic characteristics publication-title: J Pediatr doi: 10.1016/S0022-3476(98)70371-3 – volume: 63 start-page: 1966 year: 2004 end-page: 1967 ident: CR23 article-title: CSF characteristics in early-onset multiple sclerosis publication-title: Neurology – volume: 70 start-page: A136 issue: Suppl1 year: 2008 ident: CR2 article-title: Pediatric MS onset: a distinct phenotype influenced by ethnicity? publication-title: Neurology – volume: 69 start-page: 381 year: 2007 end-page: 388 ident: CR37 article-title: Childhood sun exposure influences risk of multiple sclerosis in monozygotic twins publication-title: Neurology doi: 10.1212/01.wnl.0000268266.50850.48 – volume: 42 start-page: 1692 year: 2006 end-page: 1698 ident: CR28 article-title: Pubertal development predicts resistance to infection and reinfection with Schistosoma japonicum publication-title: Clin Infect Dis doi: 10.1086/504326 – volume: 111 start-page: 241 year: 2003 end-page: 250 ident: CR29 article-title: Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses publication-title: J Clin Invest – volume: 130 start-page: 2589 year: 2007 end-page: 2595 ident: CR36 article-title: Parental smoking at home and the risk of childhood-onset multiple sclerosis in children publication-title: Brain doi: 10.1093/brain/awm198 – volume: 161 start-page: 1176 year: 2007 end-page: 1182 ident: CR34 article-title: Hepatitis B vaccination and the risk of childhood-onset multiple sclerosis publication-title: Arch Pediatr Adolesc Med doi: 10.1001/archpedi.161.12.1176 – volume: 63 start-page: 390 year: 2006 end-page: 396 ident: CR5 article-title: Brain abnormalities in neuromyelitis optica publication-title: Arch Neurol. doi: 10.1001/archneur.63.3.390 – volume: 50 start-page: 121 year: 2001 end-page: 127 ident: CR20 article-title: Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis publication-title: Ann Neurol doi: 10.1002/ana.1032 – volume: 190 start-page: 157 year: 2007 end-page: 164 ident: CR45 article-title: CCL5 and CCR5 genotypes modify clinical, radiological and pathological features of multiple sclerosis publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2007.08.005 – ident: CR31 – volume: 68 start-page: S7 year: 2007 end-page: S12 ident: CR1 article-title: Consensus definitions proposed for pediatric multiple sclerosis and related disorders publication-title: Neurology doi: 10.1212/01.wnl.0000259422.44235.a8 – volume: 130 start-page: 1105 year: 2007 end-page: 1110 ident: CR35 article-title: Hepatitis B vaccine and risk of relapse after a first childhood episode of CNS inflammatory demyelination publication-title: Brain doi: 10.1093/brain/awl368 – volume: 248 start-page: 304 year: 2001 end-page: 310 ident: CR46 article-title: HLA-DRB1 and disease outcome in multiple sclerosis publication-title: J Neurol doi: 10.1007/s004150170205 – volume: 126 start-page: 770 year: 2003 end-page: 782 ident: CR25 article-title: Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process publication-title: Brain doi: 10.1093/brain/awg081 – volume: 63 start-page: 401 year: 2008 end-page: 405 ident: CR24 article-title: Lesion distribution in children with clinically isolated syndromes publication-title: Ann Neurol doi: 10.1002/ana.21322 – ident: CR41 – volume: 66 start-page: 1235 year: 2006 end-page: 1240 ident: CR40 article-title: Does multiple sclerosis-associated disability differ between races? publication-title: Neurology doi: 10.1212/01.wnl.0000208505.81912.82 – volume: 356 start-page: 2603 year: 2007 end-page: 2613 ident: CR6 article-title: Natural history of multiple sclerosis with childhood onset publication-title: N Engl J Med doi: 10.1056/NEJMoa067597 – volume: 375 start-page: 57 year: 2007 end-page: 62 ident: CR44 article-title: CRYAB promoter polymorphisms: influence on multiple sclerosis susceptibility and clinical presentation publication-title: Clin Chim Acta doi: 10.1016/j.cca.2006.06.017 – volume: 59 start-page: 1922 year: 2002 end-page: 1928 ident: CR15 article-title: Course and prognosis in early-onset MS: comparison with adult-onset forms publication-title: Neurology – ident: 67_CR16 – ident: 67_CR41 – volume: 375 start-page: 57 year: 2007 ident: 67_CR44 publication-title: Clin Chim Acta doi: 10.1016/j.cca.2006.06.017 – volume: 53 start-page: 478 year: 1999 ident: 67_CR12 publication-title: Neurology doi: 10.1212/WNL.53.3.478 – volume: 25 start-page: S323 issue: Suppl4 year: 2004 ident: 67_CR13 publication-title: Neurol Sci doi: 10.1007/s10072-004-0334-0 – volume: 111 start-page: 241 year: 2003 ident: 67_CR29 publication-title: J Clin Invest doi: 10.1172/JCI200316721 – volume: 7 start-page: 2 year: 2006 ident: 67_CR26 publication-title: BMC Immunol doi: 10.1186/1471-2172-7-2 – volume: 69 start-page: 381 year: 2007 ident: 67_CR37 publication-title: Neurology doi: 10.1212/01.wnl.0000268266.50850.48 – ident: 67_CR22 doi: 10.1212/01.wnl.0000326896.66714.ae – ident: 67_CR32 – volume: 161 start-page: 1176 year: 2007 ident: 67_CR34 publication-title: Arch Pediatr Adolesc Med doi: 10.1001/archpedi.161.12.1176 – volume: 25 start-page: S346 issue: Suppl4 year: 2004 ident: 67_CR9 publication-title: Neurol Sci doi: 10.1007/s10072-004-0346-9 – volume: 111 start-page: 359 year: 1987 ident: 67_CR8 publication-title: J Pediatr doi: 10.1016/S0022-3476(87)80454-7 – volume: 59 start-page: 1006 year: 2002 ident: 67_CR14 publication-title: Neurology doi: 10.1212/WNL.59.7.1006 – volume: 68 start-page: S7 year: 2007 ident: 67_CR1 publication-title: Neurology doi: 10.1212/01.wnl.0000259422.44235.a8 – volume: 16 start-page: 550 year: 2007 ident: 67_CR27 publication-title: Lupus doi: 10.1177/0961203307080636 – volume: 126 start-page: 770 year: 2003 ident: 67_CR25 publication-title: Brain doi: 10.1093/brain/awg081 – volume: 9 start-page: 293 year: 2003 ident: 67_CR38 publication-title: Mult Scler doi: 10.1191/1352458503ms909oa – volume: 104 start-page: 20896 year: 2007 ident: 67_CR47 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.0707731105 – volume: 50 start-page: 121 year: 2001 ident: 67_CR20 publication-title: Ann Neurol doi: 10.1002/ana.1032 – volume: 130 start-page: 2589 year: 2007 ident: 67_CR36 publication-title: Brain doi: 10.1093/brain/awm198 – volume: 32 start-page: 625 year: 2007 ident: 67_CR17 publication-title: Dev Neuropsychol doi: 10.1080/87565640701375872 – ident: 67_CR31 doi: 10.1038/nm1715 – volume: 42 start-page: 1692 year: 2006 ident: 67_CR28 publication-title: Clin Infect Dis doi: 10.1086/504326 – volume: 27 start-page: 869 year: 2003 ident: 67_CR30 publication-title: Int J Obes Relat Metab Disord doi: 10.1038/sj.ijo.0802328 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: 67_CR43 publication-title: Neurology – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: 67_CR33 publication-title: Neurology – volume: 132 start-page: 735 year: 1998 ident: 67_CR11 publication-title: J Pediatr doi: 10.1016/S0022-3476(98)70371-3 – ident: 67_CR18 – volume: 63 start-page: 98 year: 2008 ident: 67_CR48 publication-title: Ann Neurol doi: 10.1002/ana.21244 – volume: 63 start-page: 390 year: 2006 ident: 67_CR5 publication-title: Arch Neurol. doi: 10.1001/archneur.63.3.390 – volume: 66 start-page: 1235 year: 2006 ident: 67_CR40 publication-title: Neurology doi: 10.1212/01.wnl.0000208505.81912.82 – ident: 67_CR4 – volume: 6 start-page: 773 year: 2007 ident: 67_CR7 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(07)70196-5 – volume: 86 start-page: 280 year: 1992 ident: 67_CR10 publication-title: Acta Neurol Scand doi: 10.1111/j.1600-0404.1992.tb05086.x – volume: 130 start-page: 1105 year: 2007 ident: 67_CR35 publication-title: Brain doi: 10.1093/brain/awl368 – volume: 190 start-page: 157 year: 2007 ident: 67_CR45 publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2007.08.005 – volume: 248 start-page: 304 year: 2001 ident: 67_CR46 publication-title: J Neurol doi: 10.1007/s004150170205 – volume: 63 start-page: 401 year: 2008 ident: 67_CR24 publication-title: Ann Neurol doi: 10.1002/ana.21322 – volume: 70 start-page: A136 issue: Suppl1 year: 2008 ident: 67_CR2 publication-title: Neurology – volume: 63 start-page: 2039 year: 2004 ident: 67_CR39 publication-title: Neurology doi: 10.1212/01.WNL.0000145762.60562.5D – ident: 67_CR19 – volume: 62 start-page: 806 year: 2004 ident: 67_CR21 publication-title: Neurology doi: 10.1212/01.WNL.0000113723.36715.A6 – volume: 68 start-page: S54 issue: 16Suppl2 year: 2007 ident: 67_CR49 publication-title: Neurology doi: 10.1212/01.wnl.0000259407.40023.ab – volume: 356 start-page: 2603 year: 2007 ident: 67_CR6 publication-title: N Engl J Med doi: 10.1056/NEJMoa067597 – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: 67_CR3 publication-title: Neurology – volume: 59 start-page: 1922 year: 2002 ident: 67_CR15 publication-title: Neurology doi: 10.1212/01.WNL.0000036907.37650.8E – volume: 70 start-page: A135 issue: Suppl1 year: 2008 ident: 67_CR42 publication-title: Neurology – volume: 63 start-page: 1966 year: 2004 ident: 67_CR23 publication-title: Neurology doi: 10.1212/01.WNL.0000144352.67102.BC – reference: 9580781 - J Pediatr. 1998 Apr;132(4):735-7 – reference: 1414248 - Acta Neurol Scand. 1992 Sep;86(3):280-4 – reference: 17827175 - Brain. 2007 Oct;130(Pt 10):2589-95 – reference: 12499484 - Neurology. 2002 Dec 24;59(12):1922-8 – reference: 17711887 - Lupus. 2007;16(8):550-5 – reference: 15007138 - Neurology. 2004 Mar 9;62(5):806-8 – reference: 18087043 - Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20896-901 – reference: 15596747 - Neurology. 2004 Dec 14;63(11):2039-45 – reference: 15727231 - Neurol Sci. 2004 Nov;25 Suppl 4:S346-9 – reference: 12814178 - Mult Scler. 2003 Jun;9(3):293-8 – reference: 15727226 - Neurol Sci. 2004 Nov;25 Suppl 4:S323-5 – reference: 12861226 - Int J Obes Relat Metab Disord. 2003 Aug;27(8):869-74 – reference: 17931122 - Dev Neuropsychol. 2007;32(2):625-44 – reference: 17646631 - Neurology. 2007 Jul 24;69(4):381-8 – reference: 17582070 - N Engl J Med. 2007 Jun 21;356(25):2603-13 – reference: 11456302 - Ann Neurol. 2001 Jul;50(1):121-7 – reference: 16533966 - Arch Neurol. 2006 Mar;63(3):390-6 – reference: 17438239 - Neurology. 2007 Apr 17;68(16 Suppl 2):S54-65 – reference: 11374095 - J Neurol. 2001 Apr;248(4):304-10 – reference: 17276994 - Brain. 2007 Apr;130(Pt 4):1105-10 – reference: 18306242 - Ann Neurol. 2008 Mar;63(3):401-5 – reference: 17884183 - J Neuroimmunol. 2007 Oct;190(1-2):157-64 – reference: 12531880 - J Clin Invest. 2003 Jan;111(2):241-50 – reference: 10449107 - Neurology. 1999 Aug 11;53(3):478-84 – reference: 17932975 - Ann Neurol. 2008 Jan;63(1):98-111 – reference: 17689148 - Lancet Neurol. 2007 Sep;6(9):773-81 – reference: 16636241 - Neurology. 2006 Apr 25;66(8):1235-40 – reference: 3625402 - J Pediatr. 1987 Sep;111(3):359-63 – reference: 16705573 - Clin Infect Dis. 2006 Jun 15;42(12):1692-8 – reference: 15557527 - Neurology. 2004 Nov 23;63(10):1966-7 – reference: 18056563 - Arch Pediatr Adolesc Med. 2007 Dec;161(12):1176-82 – reference: 17010329 - Clin Chim Acta. 2007 Jan;375(1-2):57-62 – reference: 12370453 - Neurology. 2002 Oct 8;59(7):1006-10 – reference: 18824673 - Neurology. 2008 Sep 30;71(14):1090-3 – reference: 16504066 - BMC Immunol. 2006 Feb 22;7:2 – reference: 17438241 - Neurology. 2007 Apr 17;68(16 Suppl 2):S7-12 – reference: 12615637 - Brain. 2003 Apr;126(Pt 4):770-82 |
| SSID | ssj0020079 |
| Score | 1.9408822 |
| SecondaryResourceType | review_article |
| Snippet | Diagnosing multiple sclerosis (MS) in a child is challenging because of the limited diagnostic criteria and their overlap with acute disseminated... |
| SourceID | proquest pubmed crossref springer |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 434 |
| SubjectTerms | Adolescent Age of Onset Brain - pathology Child Diagnosis, Differential Disease Progression Encephalomyelitis, Acute Disseminated - diagnosis Ethnic Groups - statistics & numerical data Female Humans Magnetic Resonance Imaging Male Medical treatment Medicine Medicine & Public Health Multiple sclerosis Multiple Sclerosis - diagnosis Multiple Sclerosis - drug therapy Multiple Sclerosis - epidemiology Multiple Sclerosis - pathology Multiple Sclerosis - psychology Multiple Sclerosis, Relapsing-Remitting - epidemiology Neurology Neuromyelitis Optica - diagnosis Neurosciences Phenotype Quality of Life Risk Factors |
| SummonAdditionalLinks | – databaseName: SpringerLINK Contemporary 1997-Present dbid: RSV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LSwMxEA5SRbz4fqz1sQdPSmC3yWaTo4jFgxbxUXpbMmkCBWml2_r7nWz3gVQFPe_s7GQzmUcmmY-QC0A30Imdo2jpBOWMWwqRjqjT6F-cV6ICOqF_n_Z6cjBQj-U97rw67V6VJAtL3Vx2w9TC34KW1JtYiinPKno76fEanp77dZaFtKpokuq3jVAlq1Lmdyy-OqOlCHOpOlo4ne7Wv8TdJptljBleL5Rih6zY8S5Zfyir6HvkpMbnCKvzhGGOlCjjKN8nr93bl5s7WqIkUMOEmlEjUhsBY6mWqev4DlYQDYVKhi6GJAHNLFccmHEaQzXQHBIrNABLItDOMGAHpDWejO0RCQHS2AppOLPIxcQgMDrhRqcJYNjHTECi6ndlpmwh7pEs3rKm-bEfdVZAW-Koszggl_Ur74v-Gb8Rt6s5yMqllGcyVSL1ligg5_VTXAO-sKHHdjLPM6E450qqgBwuJq75lPQQhBI5X1Wz1HD-UY7jP1G3yUZ1iCSKT0hrNp3bU7JmPmajfHpWKOcniVXahg priority: 102 providerName: Springer Nature |
| Title | Pediatric multiple sclerosis |
| URI | https://link.springer.com/article/10.1007/s11910-008-0067-1 https://www.ncbi.nlm.nih.gov/pubmed/18713581 https://www.proquest.com/docview/879673073 https://www.proquest.com/docview/69444989 |
| Volume | 8 |
| WOSCitedRecordID | wos000258914200011&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1534-6293 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0020079 issn: 1528-4042 databaseCode: 7X7 dateStart: 20010101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1534-6293 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0020079 issn: 1528-4042 databaseCode: BENPR dateStart: 20010101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Psychology Database customDbUrl: eissn: 1534-6293 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0020079 issn: 1528-4042 databaseCode: M2M dateStart: 20010101 isFulltext: true titleUrlDefault: https://www.proquest.com/psychology providerName: ProQuest – providerCode: PRVAVX databaseName: SpringerLink customDbUrl: eissn: 1534-6293 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0020079 issn: 1528-4042 databaseCode: RSV dateStart: 20010201 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT8MwDLZ4CXHh_RiDsQMnUES7pHmcECAQBzZN46HdqjhLJSS0AR38fpyu3YQQXLhEqpqmluPYTuz4AzhGMgOtOMsYaTrJBBeeYWQjllmyL1kQogI64elOdTq63zfdMjcnL9MqK51YKOrByIUz8jOtjFRBIM9f31gAjQrB1RJBYx4WA2p2EHPVn-23yPyZolxqOEAi4ayCmsXNOdqnhCvVmgV9zeLvZumHr_kjTlqYn5u1fxK-Dqul39m8mAjKBsz54SYst8vI-hYcTDE7mlWOYTOnnkTtc74NjzfXD1e3rEROYI5LM2ZOKh8h58pqlbVCVSuMBtIkgyzGJEHLvTACucssuW9oBSZeWkSeRGgzx5HvwMJwNPR70ERUsZfaCe5pFBejJI9FOKsSJFeQuxpEFeNSV5YVD-gWL-msIHLgdVrAXRKv07gGJ9NPXic1Nf7qXK_YmpbLK0-nPK3B0fQtrYsQ7LBDP_rIU2mEEEabGuxOpnD2Kx1gCTWNfFrN6WzkX-nY_5OOOqxUiSRRfAAL4_cPfwhL7nP8nL83CrEsWt2AxcvrTrdHT-1Wm9re_dMX10_pOQ |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Pb9MwFH8a2wRcGAMGZYPlABeQRVI7dnyYpmljarW24jBQb8HPdaRKU1uWjmkfat9xz2ncClXrrQfOcV6svP9-z-8H8AnJDTSTomBk6SQTXDiGsYlZYci_FF6IKuiEXx3V62X9vv6xAffhLoxvqww2sTLUg7H1Z-TfMqWl8gJ5PPnDPGiUL64GBI2ZVFy4u1vK2Mqj9hmx93Ozef798rTFalABZrnUU2alcjFyrkymiqYf-ITxQOp0UCSYpmi4E1ogt4WhyAaNwNRJg8jTGE1hOXKi-wS2yIwrn-up_iK_I3erq_Gs_sCKlCEUUaubepQX-SvcGfP-gSX_usGl2HapLlu5u_Od_-xHvYQXdVwdncwUYRc23OgVPO3WnQOv4WCOSRKFHsqopJX0d4blG_i5lr3tweZoPHLvIEJUiZOZFdwRFZugpIhMWKNSpFCX2wbEgVG5rceme_SOq3wx8NnzNq_gPIm3edKAL_NXJrOZIasW7wc25rX5KPM5DxtwOH9Keu-LOWbkxjdlLrUQQme6AW9nIrP4VOZhFzOi_DXI0ILyo_t4v3Ifh_Csddnt5J1272IfnoemmTg5gM3p9Y37ANv273RYXn-sVCKC3-sWrQfYYEQF |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1NT9wwEB1RQIhLS2mB5aPk0F5aWSSxY8eHqqqAVRGw4tBW3FKP15aQ0C6Qhao_rf-OcTbOqkJw49BznImVeZ4Ze8bzAN4juYE8856RpZNMcOEYpiZl3pB_8QFEDXXCzxM1GJTn5_psDv7GuzChrDLaxMZQD8c2nJHvlUpLFQC559uqiLOD_peraxYIpEKiNbJpTBFy7P78pt1b_fnogFT9Ic_7h9_3v7GWYIBZLvWEWalcipwrUyqfh-ZPmA6lLoY-w6JAw53QArn1hqIcNAILJw0iL1I03nLkJPcFLChBYUeoGsxPu70euV7dtGoNh1e0MGJCtbm1R3ukcJ27ZMFXsOxfl_ggzn2Qo21cX__Vf_zTVuBlG28nX6cL5DXMudEqLJ22FQVvYLvjKklibWVS00j6Uxf1W_jxLHNbg_nReOQ2IEFUmZOlFdyRFJuhpEhNWKMKpBCY2x6kUWmVbdupB1aPy2rWCDrouWpoPknPVdaDj90rV9NeIk8N3ooqrVqzUledPnuw2z0lexCSPGbkxrd1JbUQQpe6B-tT-Mw-VQY6xpIkf4p4mkl-dB6bT85jF5YIUdXJ0eB4C5ZjLU2abcP85ObW7cCivZtc1DfvmtWRwK_nRtY9qVNMyA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pediatric+multiple+sclerosis&rft.jtitle=Current+neurology+and+neuroscience+reports&rft.au=Chabas%2C+Dorothee&rft.au=Strober%2C+Jonathan&rft.au=Waubant%2C+Emmanuelle&rft.date=2008-09-01&rft.eissn=1534-6293&rft.volume=8&rft.issue=5&rft.spage=434&rft_id=info:doi/10.1007%2Fs11910-008-0067-1&rft_id=info%3Apmid%2F18713581&rft.externalDocID=18713581 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1528-4042&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1528-4042&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1528-4042&client=summon |