Evaluating the Sensitivity and Specificity of Promising Circulating Biomarkers to Diagnose Liver Injury in Humans

Early diagnosis of drug-induced liver injury (DILI) continues to be a major hurdle during drug development and postmarketing. The objective of this study was to evaluate the diagnostic performance of promising biomarkers of liver injury-glutamate dehydrogenase (GLDH), cytokeratin-18 (K18), caspase-c...

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Vydané v:	Toxicological sciences Ročník 181; číslo 1; s. 23
Hlavní autori:	Llewellyn, Heather P, Vaidya, Vishal S, Wang, Zhenyu, Peng, Qinghai, Hyde, Craig, Potter, David, Wang, Jianying, Zong, Qing, Arat, Seda, Martin, Matt, Masek-Hammerman, Katherine, Warner, Roscoe, Johnson, Kent, Kullak-Ublick, Gerd A, Aithal, Guruprasad P, Dear, James W, Ramaiah, Shashi K
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 27.04.2021
Predmet:	diagnosis microRNA glutamate dehydrogenase keratin-18 liver
ISSN:	1096-0929, 1096-0929
On-line prístup:	Zistit podrobnosti o prístupe
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