Regulation of voltage-gated potassium channels by PI(4,5)P2

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) regulates activities of numerous ion channels including inwardly rectifying potassium (K(ir)) channels, KCNQ, TRP, and voltage-gated calcium channels. Several studies suggest that voltage-gated potassium (K(V)) channels might be regulated by PI(4,5...

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Bibliographic Details
Published in:	The Journal of general physiology Vol. 140; no. 2; p. 189
Main Authors:	Kruse, Martin, Hammond, Gerald R V, Hille, Bertil
Format:	Journal Article
Language:	English
Published:	United States 01.08.2012
Subjects:	Cell Line Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism Fluorescence Resonance Energy Transfer Humans Kv Channel-Interacting Proteins - metabolism Muscarinic Agonists - pharmacology Nerve Tissue Proteins - metabolism Patch-Clamp Techniques Phosphatidylinositol 4,5-Diphosphate - metabolism Phosphoric Monoester Hydrolases - antagonists & inhibitors Phosphoric Monoester Hydrolases - genetics Phosphoric Monoester Hydrolases - metabolism Potassium Channels - metabolism Potassium Channels, Inwardly Rectifying - metabolism Potassium Channels, Voltage-Gated - metabolism Receptor, Muscarinic M1 - agonists Receptor, Muscarinic M1 - metabolism Recombinant Proteins - analysis Sirolimus - pharmacology Zebrafish Proteins - chemistry Zebrafish Proteins - metabolism
ISSN:	1540-7748, 1540-7748
Online Access:	Get more information
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