Response to Periodontal Therapy in Diabetics and Smokers

Diabetics and smokers are two patient groups at high risk for periodontal disease who also exhibit impaired wound healing and, therefore, constitute two different groups in whom the relationship between host-parasite interaction, outcome of periodontal therapy, and systemic factors is best represent...

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Bibliographic Details
Published in:Journal of periodontology (1970) Vol. 67 Suppl 10S; no. 10 Suppl; p. 1094
Main Authors: Grossi, Sara G, Skrepcinski, Fred B, DeCaro, Thomas, Zambon, Joseph J, Cummins, Diane, Genco, Robert J
Format: Journal Article
Language:English
Published: United States 01.10.1996
Subjects:
Host response
risk factors
wound healing
periodontal diseases/therapy
diabetes mellitus/complications
smoking/adverse effects
ISSN:1943-3670, 0022-3492, 1943-3670
Online Access:Get more information
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Summary:Diabetics and smokers are two patient groups at high risk for periodontal disease who also exhibit impaired wound healing and, therefore, constitute two different groups in whom the relationship between host-parasite interaction, outcome of periodontal therapy, and systemic factors is best represented. The results of two independent clinical trials involving treatment of periodontal disease in diabetics and smokers are presented. A new treatment regimen-for the management of periodontal disease associated with diabetes mellitus is proposed. This treatment approach incorporates both antimicrobial agents and pharmacological modulation of the host response. Elimination of periodontal infection and reduction of periodontal inflammation in diabetic patients resulted in a significant short-term reduction in the concentration of glycosylated hemoglobin (HbA ). Control of chronic infections and modulation of the host response offer a new therapeutic approach in the management of patients with both diabetes and periodontal disease. The effect of smoking on periodontal healing is also discussed. The clinical and microbiological response of smokers to non-surgical periodontal therapy is compared to non-smokers. In addition, possible mechanisms whereby diabetes mellitus and cigarette smoking increase the severity of periodontal disease are discussed. J Periodontol 1996;67:1094-1102.
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ISSN:1943-3670
0022-3492
1943-3670
DOI:10.1902/jop.1996.67.10s.1094