Application of whole-genome sequencing for distinguishing relapse from reinfection in tuberculosis patients from Lithuania

•Reinfection accounted for 40% of recurrent tuberculosis (TB) cases.•Half of the TB treatment failures were found to be reinfections.•Only 55% of patients were correctly differentiated as relapse or treatment failure.•Extensively drug-resistant TB emerged undetected due to limited diagnostics. Tuber...

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Bibliographic Details
Published in:	International journal of infectious diseases Vol. 162; p. 108203
Main Authors:	Vasiliauskaitė, Laima, Zinola, Alma, Marco, Federico Di, Davidavičienė, Valerija Edita, Nakčerienė, Birutė, Vaitulionytė, Agnė, Cirillo, Daniela Maria, Kačergius, Tomas
Format:	Journal Article
Language:	English
Published:	Canada Elsevier Ltd 01.01.2026 Elsevier
Subjects:	Infectious Disease Pulmonary/Respiratory Recurrence Reinfection Relapse Tuberculosis Whole-genome sequencing Recurrence Relapse Tuberculosis Reinfection Whole-genome sequencing recurrence reinfection relapse whole-genome sequencing
ISSN:	1201-9712, 1878-3511, 1878-3511
Online Access:	Get full text
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