Mendelian and polygenic inheritance of intelligence: A common set of causal genes? Using next-generation sequencing to examine the effects of 168 intellectual disability genes on normal-range intelligence

Despite twin and family studies having demonstrated a substantial heritability of individual differences in intelligence, no genetic variants have been robustly associated with normal-range intelligence to date. This is largely ascribed to the high polygenicity of intelligence, i.e., to its being su...

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Vydáno v:	Intelligence (Norwood) Ročník 49; s. 10 - 22
Hlavní autoři:	Franić, Sanja, Dolan, Conor V., Broxholme, John, Hu, Hao, Zemojtel, Tomasz, Davies, Garreth E., Nelson, Kelly A., Ehli, Erik A., Pool, René, Hottenga, Jouke-Jan, Ropers, H.-Hilger, Boomsma, Dorret I.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Elsevier Inc 01.03.2015 Elsevier Science Ltd
Témata:	Ascription Biological variation Candidates Family research Family studies Genes Genetics Genomics Genotype & phenotype Heritability Individual differences Inheritance Inheritance and succession Intellectual disabilities Intelligence Intelligence tests Learning disabilities Mutation Next-generation sequencing People with disabilities Phenotypes Polygenic prediction Variants Genetics Next-generation sequencing Intelligence Polygenic prediction
ISSN:	0160-2896, 1873-7935
On-line přístup:	Získat plný text
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