Is there a role for gut microbiota in type 1 diabetes pathogenesis?

Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by insufficient insulin production due to the destruction of insulin secreting β-cells in the Langerhans islets. A variety of factors, including chemicals, viruses, commensal bacteria and diet have been proposed to contribute to t...

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Bibliographic Details
Published in:	Annals of medicine (Helsinki) Vol. 49; no. 1; pp. 11 - 22
Main Authors:	Bibbò, Stefano, Dore, Maria Pina, Pes, Giovanni Mario, Delitala, Giuseppe, Delitala, Alessandro P.
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 02.01.2017
Subjects:	Animals autoimmunity Autoimmunity - physiology Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - microbiology Diabetes Mellitus, Type 1 - physiopathology Diet - adverse effects Dysbiosis Dysbiosis - immunology Gastrointestinal Microbiome - immunology gut permeability Humans Insulin-Secreting Cells - immunology Insulin-Secreting Cells - pathology Intestines - immunology Intestines - microbiology Microbiota Models, Animal Permeability prevention probiotic Probiotics - therapeutic use therapy type 1 diabetes mellitus type 1 diabetes mellitus probiotic autoimmunity gut permeability therapy Dysbiosis prevention
ISSN:	0785-3890, 1365-2060, 1365-2060
Online Access:	Get full text
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