The management of asthma in the phenotype and biomarker era: The proposal of a new diagnostic-therapeutic model

Treatment goals in asthma patients are the achievement of a good control of symptoms and the reduction of the risk of exacerbation. However, a "one-size-fits-all" therapeutic strategy is no longer appropriate to effectively pursue these goals, due to the heterogeneity of asthma. To make th...

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Vydáno v:The Journal of asthma Ročník 53; číslo 7; s. 665 - 667
Hlavní autoři: Blasi, Francesco, Bettoncelli, Germano, Canonica, Giorgio Walter, Centanni, Stefano, Crimi, Nunzio, DiMaria, Giuseppe, Gasparini, Stefano, Gentili, Gilberto, Girbino, Giuseppe, Mereu, Carlo, Minghetti, Paola, Nardini, Stefano, Paggiaro, Pierluigi, Papi, Alberto, Pistolesi, Massimo, Rossi, Andrea
Médium: Journal Article
Jazyk:angličtina
Vydáno: England Taylor & Francis 01.09.2016
Témata:
Asthma
Asthma - diagnosis
Biomarkers
clinical decision
Comorbidity
diagnosis
Disease Management
Humans
management
Phenotype
therapy
phenotype
management
clinical decision
therapy
diagnosis
model
Asthma
ISSN:0277-0903, 1532-4303, 1532-4303
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Abstract Treatment goals in asthma patients are the achievement of a good control of symptoms and the reduction of the risk of exacerbation. However, a "one-size-fits-all" therapeutic strategy is no longer appropriate to effectively pursue these goals, due to the heterogeneity of asthma. To make the treatment scenario even more complex, asthma patients often present comorbidities that may alter response to therapy. In addition, adherence to asthma treatment is poor. Given this complex and heterogeneous picture, the management of asthma is highly challenging. A clear diagnostic-therapeutic model of patients' care and the definition of the specific responsibilities of different healthcare providers appear necessary to improve clinical outcomes and better allocate healthcare resources. We present here a proposal for this model.
AbstractList Treatment goals in asthma patients are the achievement of a good control of symptoms and the reduction of the risk of exacerbation. However, a "one-size-fits-all" therapeutic strategy is no longer appropriate to effectively pursue these goals, due to the heterogeneity of asthma. To make the treatment scenario even more complex, asthma patients often present comorbidities that may alter response to therapy. In addition, adherence to asthma treatment is poor. Given this complex and heterogeneous picture, the management of asthma is highly challenging. A clear diagnostic-therapeutic model of patients' care and the definition of the specific responsibilities of different healthcare providers appear necessary to improve clinical outcomes and better allocate healthcare resources. We present here a proposal for this model.
Treatment goals in asthma patients are the achievement of a good control of symptoms and the reduction of the risk of exacerbation. However, a "one-size-fits-all" therapeutic strategy is no longer appropriate to effectively pursue these goals, due to the heterogeneity of asthma. To make the treatment scenario even more complex, asthma patients often present comorbidities that may alter response to therapy. In addition, adherence to asthma treatment is poor. Given this complex and heterogeneous picture, the management of asthma is highly challenging. A clear diagnostic-therapeutic model of patients' care and the definition of the specific responsibilities of different healthcare providers appear necessary to improve clinical outcomes and better allocate healthcare resources. We present here a proposal for this model.Treatment goals in asthma patients are the achievement of a good control of symptoms and the reduction of the risk of exacerbation. However, a "one-size-fits-all" therapeutic strategy is no longer appropriate to effectively pursue these goals, due to the heterogeneity of asthma. To make the treatment scenario even more complex, asthma patients often present comorbidities that may alter response to therapy. In addition, adherence to asthma treatment is poor. Given this complex and heterogeneous picture, the management of asthma is highly challenging. A clear diagnostic-therapeutic model of patients' care and the definition of the specific responsibilities of different healthcare providers appear necessary to improve clinical outcomes and better allocate healthcare resources. We present here a proposal for this model.
Author Crimi, Nunzio
Minghetti, Paola
Gasparini, Stefano
Nardini, Stefano
Mereu, Carlo
Papi, Alberto
Gentili, Gilberto
Pistolesi, Massimo
Girbino, Giuseppe
Bettoncelli, Germano
Paggiaro, Pierluigi
Canonica, Giorgio Walter
DiMaria, Giuseppe
Blasi, Francesco
Centanni, Stefano
Rossi, Andrea
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SubjectTerms Asthma
Asthma - diagnosis
Biomarkers
clinical decision
Comorbidity
diagnosis
Disease Management
Humans
management
Phenotype
therapy
Title The management of asthma in the phenotype and biomarker era: The proposal of a new diagnostic-therapeutic model
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