Isolation, characterization and in silico study of propenamide alkaloids from Hymenoepmecis bicolor poison against active μ-opioid receptor

Some insects produce venoms to defend against predators and directly interact with opioid receptors. In the present study, it was identified two alkaloids in the wasp venom species Hymenoepimecis bicolor. It was demonstrated that these could act as potential inhibitors of opioid receptors through th...

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Bibliographic Details

Published in:	Journal of biomolecular structure & dynamics Vol. 41; no. 24; pp. 14621 - 14637
Main Authors:	Marques da Fonseca, Aluísio, Freire da Silva, Ananias, Barbosa da Silva, Francisco Lennon, Caluaco, Bernardino Joaquim, Gaieta, Eduardo Menezes, Nunes da Rocha, Matheus, Colares, Regilany Paulo, Sobczak, Jober Fernando, Marinho, Gabrielle Silva, dos Santos, Hélcio Silva, Marinho, Emmanuel Silva
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 29.12.2023
Subjects:	Alkaloids - pharmacology arthropod chemical composition computational simulation Morphine - chemistry Morphine - pharmacology Poisons Receptors, Opioid Wasp computational simulation arthropod chemical composition Wasp
ISSN:	0739-1102, 1538-0254, 1538-0254
Online Access:	Get full text
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