Isolation, characterization and in silico study of propenamide alkaloids from Hymenoepmecis bicolor poison against active μ-opioid receptor

Some insects produce venoms to defend against predators and directly interact with opioid receptors. In the present study, it was identified two alkaloids in the wasp venom species Hymenoepimecis bicolor. It was demonstrated that these could act as potential inhibitors of opioid receptors through th...

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Veröffentlicht in:	Journal of biomolecular structure & dynamics Jg. 41; H. 24; S. 14621 - 14637
Hauptverfasser:	Marques da Fonseca, Aluísio, Freire da Silva, Ananias, Barbosa da Silva, Francisco Lennon, Caluaco, Bernardino Joaquim, Gaieta, Eduardo Menezes, Nunes da Rocha, Matheus, Colares, Regilany Paulo, Sobczak, Jober Fernando, Marinho, Gabrielle Silva, dos Santos, Hélcio Silva, Marinho, Emmanuel Silva
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Taylor & Francis 29.12.2023
Schlagworte:	Alkaloids - pharmacology arthropod chemical composition computational simulation Morphine - chemistry Morphine - pharmacology Poisons Receptors, Opioid Wasp computational simulation arthropod chemical composition Wasp
ISSN:	0739-1102, 1538-0254, 1538-0254
Online-Zugang:	Volltext
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