A phenomenological model of EEG based on the dynamics of a stochastic Duffing-van der Pol oscillator network

•EEG can be represented as the output of Duffing-van der Pol oscillator model.•Eyes-closed and eyes-open EEG data are distinct realizations of the model.•Stochastic models are better in terms of power spectra and information entropy.•Model may be used for characterization of distinct brain states an...

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Vydáno v:Biomedical signal processing and control Ročník 15; s. 1 - 10
Hlavní autoři: Ghorbanian, P., Ramakrishnan, S., Whitman, A., Ashrafiuon, H.
Médium: Journal Article
Jazyk:angličtina
Vydáno: Elsevier Ltd 01.01.2015
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ISSN:1746-8094
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Abstract •EEG can be represented as the output of Duffing-van der Pol oscillator model.•Eyes-closed and eyes-open EEG data are distinct realizations of the model.•Stochastic models are better in terms of power spectra and information entropy.•Model may be used for characterization of distinct brain states and disorders. In this work, we propose a novel phenomenological model of the EEG signal based on the dynamics of a coupled Duffing-van der Pol oscillator network. An optimization scheme is adopted to match data generated from the model with clinically obtained EEG data from subjects under resting eyes-open (EO) and eyes-closed (EC) conditions. It is shown that a coupled system of two Duffing-van der Pol oscillators with optimized parameters yields signals with characteristics that match those of the EEG in both the EO and EC cases. The results, which are reinforced using statistical analysis, show that the EEG recordings under EC and EO resting conditions are clearly distinct realizations of the same underlying model occurring due to parameter variations with qualitatively different nonlinear dynamic characteristics. In addition, the interplay between noise and nonlinearity is addressed and it is shown that, for appropriately chosen values of noise intensity in the model, very good agreement exists between the model output and the EEG in terms of the power spectrum as well as Shannon entropy. In summary, the results establish that an appropriately tuned stochastic coupled nonlinear oscillator network such as the Duffing-van der Pol system could provide a useful framework for modeling and analysis of the EEG signal. In turn, design of algorithms based on the framework has the potential to positively impact the development of novel diagnostic strategies for brain injuries and disorders.
AbstractList •EEG can be represented as the output of Duffing-van der Pol oscillator model.•Eyes-closed and eyes-open EEG data are distinct realizations of the model.•Stochastic models are better in terms of power spectra and information entropy.•Model may be used for characterization of distinct brain states and disorders. In this work, we propose a novel phenomenological model of the EEG signal based on the dynamics of a coupled Duffing-van der Pol oscillator network. An optimization scheme is adopted to match data generated from the model with clinically obtained EEG data from subjects under resting eyes-open (EO) and eyes-closed (EC) conditions. It is shown that a coupled system of two Duffing-van der Pol oscillators with optimized parameters yields signals with characteristics that match those of the EEG in both the EO and EC cases. The results, which are reinforced using statistical analysis, show that the EEG recordings under EC and EO resting conditions are clearly distinct realizations of the same underlying model occurring due to parameter variations with qualitatively different nonlinear dynamic characteristics. In addition, the interplay between noise and nonlinearity is addressed and it is shown that, for appropriately chosen values of noise intensity in the model, very good agreement exists between the model output and the EEG in terms of the power spectrum as well as Shannon entropy. In summary, the results establish that an appropriately tuned stochastic coupled nonlinear oscillator network such as the Duffing-van der Pol system could provide a useful framework for modeling and analysis of the EEG signal. In turn, design of algorithms based on the framework has the potential to positively impact the development of novel diagnostic strategies for brain injuries and disorders.
Author Ramakrishnan, S.
Ghorbanian, P.
Ashrafiuon, H.
Whitman, A.
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  surname: Ashrafiuon
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  email: hashem.ashrafiuon@villanova.edu
  organization: Center for Nonlinear Dynamics and Control, Villanova University, Villanova, PA 19085, United States
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Keywords EEG
Stochastic dynamics
Nonlinear oscillator networks
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Snippet •EEG can be represented as the output of Duffing-van der Pol oscillator model.•Eyes-closed and eyes-open EEG data are distinct realizations of the...
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SubjectTerms EEG
Nonlinear oscillator networks
Stochastic dynamics
Title A phenomenological model of EEG based on the dynamics of a stochastic Duffing-van der Pol oscillator network
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