Human alpha-adducin gene, blood pressure, and sodium metabolism

The adducin genes contribute significantly to population variation in rat blood pressure and cell membrane sodium transport. The 460Trp mutation of the human alpha-adducin gene has been associated with hypertension, in particular hypertension sensitive to sodium restriction. We studied the relations...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Jg. 32; H. 1; S. 138
Hauptverfasser:	Kamitani, A, Wong, Z Y, Fraser, R, Davies, D L, Connor, J M, Foy, C J, Watt, G C, Harrap, S B
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.1998
Schlagworte:	Adolescent Adult Alleles Analysis of Variance Base Sequence Blood Pressure Calmodulin-Binding Proteins - genetics Cytoskeletal Proteins - genetics DNA - genetics Erythrocytes - metabolism Female Gene Frequency Genetic Variation Genotype Humans Male Middle Aged Molecular Sequence Data Mutation Oligonucleotides, Antisense - genetics Phenotype Polymerase Chain Reaction Polymorphism, Genetic Scotland Sodium - blood Sodium - metabolism Thionucleotides - genetics Scotland
ISSN:	0194-911X
Online-Zugang:	Weitere Angaben
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