Negative Symptoms and Reward Disturbances in Schizophrenia Before and After Antipsychotic Monotherapy

Background. Negative symptoms (NS) are a central part of the symptomatology of schizophrenia, which is highly correlated to the functional outcome. Disturbances of the brain reward system are suggested to be central in the pathogenesis of NS by decreasing motivation and hedonic experiences. In this...

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Bibliographic Details
Published in:	Clinical EEG and neuroscience Vol. 49; no. 1; pp. 36 - 45
Main Authors:	Nielsen, Mette Ødegaard, Rostrup, Egill, Broberg, Brian Villumsen, Wulff, Sanne, Glenthøj, Birte
Format:	Journal Article
Language:	English
Published:	Los Angeles, CA SAGE Publications 01.01.2018 SAGE PUBLICATIONS, INC
Subjects:	Adolescent Adult Antipsychotic Agents - therapeutic use Antipsychotics Apathy Brain - drug effects Brain - physiopathology Brain mapping Brain research Caudate nucleus Design Drug dosages Electroencephalography - methods Emotional behavior Functional magnetic resonance imaging Humans Learning Magnetic Resonance Imaging - methods Mental disorders Middle Aged Motivation Motivation - physiology Neostriatum Neurobiology Neuroimaging Nucleus accumbens Psychopathology Psychotropic drugs Reinforcement Reward Schizophrenia Schizophrenia - drug therapy Schizophrenia - physiopathology Short term memory Studies Young Adult fMRI schizophrenia reward system antipsychotic medication negative symptoms
ISSN:	1550-0594, 2169-5202, 2169-5202
Online Access:	Get full text
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