Cardioprotective effects of ( E )-4-hydroxy-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide: a newly synthesized coumarin hydrazone against isoproterenol-induced myocardial infarction in a rat model

The current study was carried out to evaluate the effect of pretreatment and co-treatment with a newly synthesized coumarin hydrazone, ( )-4-hydroxy-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide (hereinafter EK6), against isoproterenol-induced myocardial infarction in rats. Cha...

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Bibliographic Details
Published in:	Canadian journal of physiology and pharmacology Vol. 97; no. 10; p. 989
Main Authors:	Ghazouani, Lakhdar, Khdhiri, Emna, Elmufti, Afoua, Feriani, Anouar, Tir, Meriam, Baaziz, Intissar, Hajji, Raouf, Ben Mansour, Hedi, Ammar, Houcine, Abid, Souhir, Mnafgui, Kais
Format:	Journal Article
Language:	English
Published:	Canada 01.10.2019
Subjects:	Animals Benzopyrans - administration & dosage Benzopyrans - chemical synthesis Biomarkers - analysis Cardiotonic Agents - administration & dosage Cardiotonic Agents - chemical synthesis Coumarins - administration & dosage Coumarins - chemical synthesis Disease Models, Animal Electrocardiography Heart - drug effects Heart Rate - drug effects Humans Hydrazones - administration & dosage Hydrazones - chemical synthesis Isoproterenol - toxicity Male Myocardial Infarction - chemically induced Myocardial Infarction - diagnosis Myocardial Infarction - drug therapy Myocardium - pathology Rats Rats, Wistar Treatment Outcome dérivé de la coumarine myocardial infarction ECG cardioprotection isoprotérénol infarctus du myocarde isoproterenol coumarin derivative
ISSN:	1205-7541, 1205-7541
Online Access:	Get more information
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