Brain serotonin 2A receptor binding predicts subjective temporal and mystical effects of psilocybin in healthy humans

Psilocybin is a serotonergic psychedelic with psychoactive effects mediated by serotonin 2A receptor (5-HT2AR) activation. It produces an acute psychedelic altered state of consciousness with a unique phenomenology that can be temporally characterized by three intensity phases: onset of psychoactive...

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Vydáno v:	Journal of psychopharmacology (Oxford) Ročník 35; číslo 4; s. 459
Hlavní autoři:	Stenbæk, Dea Siggaard, Madsen, Martin Korsbak, Ozenne, Brice, Kristiansen, Sara, Burmester, Daniel, Erritzoe, David, Knudsen, Gitte Moos, Fisher, Patrick MacDonald
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.04.2021
Témata:	Adult Brain - diagnostic imaging Brain - drug effects Brain - metabolism Consciousness - drug effects Consciousness - physiology Female Hallucinogens - administration & dosage Hallucinogens - pharmacokinetics Humans Male Mysticism - psychology Outcome Assessment, Health Care Positron-Emission Tomography - methods Psilocybin - administration & dosage Psilocybin - pharmacokinetics Psychotropic Drugs - administration & dosage Psychotropic Drugs - pharmacokinetics Receptors, Serotonin, 5-HT2 - metabolism Self Concept Serotonin 5-HT2 Receptor Agonists - administration & dosage Serotonin 5-HT2 Receptor Agonists - pharmacokinetics psychedelics Serotonin 2A receptor psilocybin subjective drug intensity positron emission tomography mystical type experience
ISSN:	1461-7285, 1461-7285
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