NLC versus nanoemulsions: Effect on physiological skin parameters during regular in vivo application and impact on drug penetration

[Display omitted] Nanostructured lipid carriers (NLC) and nano-sized emulsions based on monoacyl-phosphatidylcholine (MAPL) were tested for their effect on physiological skin parameters in vivo during daily application over four weeks. The influence of the basic formulations on transepidermal water...

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Bibliographic Details
Published in:	International journal of pharmaceutics Vol. 549; no. 1-2; pp. 343 - 351
Main Authors:	Wolf, Martin, Klang, Victoria, Stojcic, Tatjana, Fuchs, Carola, Wolzt, Michael, Valenta, Claudia
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 05.10.2018
Subjects:	Administration, Cutaneous Adult Animals Confocal Raman spectroscopy Curcumin Curcumin - administration & dosage Curcumin - chemistry Curcumin - metabolism Drug Carriers Drug Compounding Electric Capacitance Emulsions Female Humans Hydrogen-Ion Concentration Male Monoacyl-phosphatidylcholine Nanoparticles Nanostructured lipid carriers Phosphatidylcholines - chemistry Sebum - metabolism Skin - metabolism Skin Absorption Sus scrofa Tape stripping Time Factors Urea - metabolism Water Loss, Insensible Young Adult SC Nanostructured lipid carriers TEWL MAPL NLC PDI CRS NMF Tape stripping Confocal Raman spectroscopy Curcumin Monoacyl-phosphatidylcholine
ISSN:	0378-5173, 1873-3476, 1873-3476
Online Access:	Get full text
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