Vascular endothelial‐cadherin stimulates syndecan‐1‐coupled insulin‐like growth factor‐1 receptor and cross‐talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis

Vascular endothelial growth factor (VEGF)‐stimulated angiogenesis depends on a cross‐talk mechanism involving VEGF receptor 2 (VEGFR2), vascular endothelial (VE)‐cadherin and the αVβ3 integrin. Because we have shown that αVβ3 integrin activation is dependent on its incorporation, along with the insu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The FEBS journal Jg. 280; H. 10; S. 2194 - 2206
Hauptverfasser:	Rapraeger, Alan C., Ell, Brian J., Roy, Madhuchhanda, Li, Xuehui, Morrison, Orrianne R., Thomas, Grant M., Beauvais, DeannaLee M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.05.2013
Schlagworte:	Animals Antibodies - metabolism Antigens, CD - metabolism Aorta - drug effects Aorta - metabolism aortic ring blocking antibodies Cadherins - antagonists & inhibitors Cadherins - metabolism Cell Adhesion Cell Movement Cells, Cultured Collagen - metabolism Endothelial Cells - drug effects Endothelial Cells - metabolism Human Umbilical Vein Endothelial Cells Humans Integrin alphaVbeta3 - metabolism Mice Neovascularization, Physiologic - drug effects Peptides - pharmacology Phosphorylation Protein Binding Protein Interaction Mapping Receptor Cross-Talk Receptors, Somatomedin - antagonists & inhibitors Receptors, Somatomedin - metabolism scratch wound Syndecan-1 - metabolism synstatin Ternary Complex Factors - metabolism Vascular Endothelial Growth Factor A - pharmacology Vascular Endothelial Growth Factor Receptor-2 - metabolism
ISSN:	1742-464X, 1742-4658, 1742-4658
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!