CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease

α-Synuclein, a key pathological component of Parkinson's disease, has been implicated in the activation of the innate and adaptive immune system. This immune activation includes microgliosis, increased inflammatory cytokines, and the infiltration of T cells into the CNS. More recently, peripher...

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Bibliographic Details
Published in:Brain (London, England : 1878) Vol. 144; no. 7; p. 2047
Main Authors: Williams, Gregory P, Schonhoff, Aubrey M, Jurkuvenaite, Asta, Gallups, Nicole J, Standaert, David G, Harms, Ashley S
Format: Journal Article
Language:English
Published: 17.08.2021
ISSN:1460-2156, 1460-2156
Online Access:Get more information
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